{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T07:32:22Z","timestamp":1774596742854,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>Abstact<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Propensity score indicates a probability of having a confounding factor. It is used to match each patient with the closest propensity score between two groups, which is known as propensity score matching. This study aimed to evaluate the gallstone\u2010related biliary events, defined as biliary colic and acute cholecystitis between coronary artery disease (<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>) and non\u2010<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> patients using propensity score matching.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort study evaluated 267 asymptomatic gallstone patients with <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> and 459 asymptomatic gallstone patients without <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> from <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2003 to <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2009 at two tertiary teaching hospitals in the <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>epublic of <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>orea. After propensity score matching, total 378 patients, including 126 in study group (with <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>) and 252 in control group (without <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>), were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a median follow\u2010up of 47 months, overall gallstone\u2010related biliary event rate was 33.5% in the study group and 27.5% in the control group. The 5\u2010year cumulative rates were 25.3% <jats:italic>versus<\/jats:italic> 17.7% in gallstone\u2010related biliary event and 10.9% <jats:italic>versus<\/jats:italic> 1.6% in acute cholecystitis (study <jats:italic>versus<\/jats:italic> control group). After propensity score adjustment, the risk of gallstone\u2010related biliary events in the <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> patients significantly increased (hazard ratio 2.11, 95% confidence interval 1.14\u20133.90, <jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.017 in matched patients).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with asymptomatic gallstones, the coexistence of <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> can increase the risk of gallstone\u2010related biliary events, particularly acute cholecystitis. Therefore, gallstone patients with <jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content> should be carefully monitored, even if they are asymptomatic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12275","type":"journal-article","created":{"date-parts":[[2013,5,22]],"date-time":"2013-05-22T11:56:46Z","timestamp":1369223806000},"page":"1578-1583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Presence of coronary artery disease increases the risk of biliary events in patients with asymptomatic gallstones"],"prefix":"10.1111","volume":"28","author":[{"given":"Yoon Suk","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Bundang Hospital  Seoungnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Eon","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Bundang Hospital  Seoungnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ban Seok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Bundang Hospital  Seoungnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung\u2010June","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Bundang Hospital  Seoungnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Bundang Hospital  Seoungnam\u2010si Gyeonggi\u2010do Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joo Kyung","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Healthcare Gangnam Center Seoul National University College of Medicine Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Hyub","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University College of Medicine Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Kon","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Seoul National University 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