{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:11:57Z","timestamp":1787015517785,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,10,22]],"date-time":"2013-10-22T00:00:00Z","timestamp":1382400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2013,11]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n Treatment outcomes are suboptimal for patients undergoing endoscopic treatment of walled\u2010off pancreatic necrosis (\n WOPN<\/jats:styled-content>\n ). The objective of this study is to identify factors that impact treatment outcomes in this patient subset.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This is a retrospective study of patients with\n WOPN<\/jats:styled-content>\n treated endoscopically over 10 years. Patients underwent placement of stents and nasocystic catheters within the necrotic cavity. In select patients, the multiple transluminal gateway technique (\n MTGT<\/jats:styled-content>\n ) was adopted to create several openings in the stomach or duodenum to facilitate drainage of necrosis. In patients with disconnected pancreatic duct syndrome (\n DPDS<\/jats:styled-content>\n ), the transmural stents were left in place indefinitely to decrease pancreatic fluid collection (\n PFC<\/jats:styled-content>\n ) recurrence.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Endoscopic treatment was successful in 53 of 76 (69.7%) patients. Treatment success was higher in patients undergoing\n MTGT<\/jats:styled-content>\n than in those in whom conventional drainage was used (94.4%\n vs<\/jats:italic>\n 62.1%,\n P<\/jats:italic>\n \u2009=\u20090.009). On multivariate logistic regression analysis, only\n MTGT<\/jats:styled-content>\n (\n OR<\/jats:styled-content>\n 15.8, 95%\n CI<\/jats:styled-content>\n 1.77\u2013140.8;\n P<\/jats:italic>\n \u2009=\u20090.01) and fewer endoscopic sessions being needed (\n OR<\/jats:styled-content>\n 4.0, 95%\n CI<\/jats:styled-content>\n 1.16\u201314.0;\n P<\/jats:italic>\n \u2009=\u20090.03) predicted treatment success.\n PFC<\/jats:styled-content>\n recurrence was significantly lower in patients with indwelling transmural stents than in patients in whom the stents were removed (0\n vs<\/jats:italic>\n 20.8%;\n P<\/jats:italic>\n \u2009=\u20090.02).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Creating multiple gateways for drainage of necrotic debris improves treatment success, and not removing the transmural stents decreases\n PFC<\/jats:styled-content>\n recurrence in patients undergoing endoscopic drainage of\n WOPN<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgh.12328","type":"journal-article","created":{"date-parts":[[2013,7,5]],"date-time":"2013-07-05T07:46:47Z","timestamp":1373010407000},"page":"1725-1732","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Factors impacting treatment outcomes in the endoscopic management of walled\u2010off pancreatic necrosis"],"prefix":"10.1111","volume":"28","author":[{"given":"Ji Young","family":"Bang","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C Mel","family":"Wilcox","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Trevino","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayapal","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shajan","family":"Peter","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Hasan","sequence":"additional","affiliation":[{"name":"Center for Interventional Endoscopy Florida Hospital Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert H.","family":"Hawes","sequence":"additional","affiliation":[{"name":"Center for Interventional Endoscopy Florida Hospital Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Varadarajulu","sequence":"additional","affiliation":[{"name":"Center for Interventional Endoscopy Florida Hospital Orlando Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,22]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1039-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00856.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000148222.09869.92"},{"key":"e_1_2_5_5_1","first-page":"2019","article-title":"AGA Institute medical position statement on acute pancreatitis","volume":"131","author":"AGA Institute Governing Board","year":"2007","journal-title":"Gastroenterology"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.05.005"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31815b6976"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200110000-00016"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b59303"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.06.061"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-011-1621-8"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-011-1795-x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.163733"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.11.041"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200307000-00023"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.06.083"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2233010680"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.03.1122"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908821"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90909-W"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.07.049"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.12.043"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.12328","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.12328","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.12328","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T18:10:00Z","timestamp":1696270200000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.12328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,22]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1111\/jgh.12328"],"URL":"https:\/\/doi.org\/10.1111\/jgh.12328","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,22]]},"assertion":[{"value":"2013-06-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}