{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:04:25Z","timestamp":1762340665274},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T00:00:00Z","timestamp":1392768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2014,3]]},"abstract":"Abstract<\/jats:title>Background and Aim<\/jats:title>Effectiveness of capsule endoscopy (CE<\/jats:styled-content>) for screening the small bowel in patients with portal hypertension (PHT<\/jats:styled-content>) has been reported. However, few reports discuss CE<\/jats:styled-content> detection of specific esophagogastric lesions related to PHT<\/jats:styled-content>. Thus, we assessed whether CE<\/jats:styled-content> is useful for detecting such lesions.<\/jats:p><\/jats:sec>Methods<\/jats:title>One hundred nineteen consecutive patients with PHT<\/jats:styled-content> comprised the study group. All had undergone esophagogastroduodenoscopy (EGD<\/jats:styled-content>) prior to CE<\/jats:styled-content>. The diagnostic yield of CE<\/jats:styled-content> for esophageal varices (EV<\/jats:styled-content>s), gastric varices (GV<\/jats:styled-content>s), and portal hypertensive gastropathy (PHG<\/jats:styled-content>) was evaluated. In addition, diagnostic yield in relation to form, location of the varices, grade, and extent of PHG was evaluated.<\/jats:p><\/jats:sec>Results<\/jats:title>EV<\/jats:styled-content>s were found by EGD<\/jats:styled-content> in 71 patients. The overall diagnostic yield of CE<\/jats:styled-content> for EV<\/jats:styled-content>s was 72% (51\/71). The diagnostic yield was significantly greater for F2\/F3 EVs than for F1 EVs (87% vs<\/jats:italic> 61%, P<\/jats:italic>\u2009=\u20090.03). The diagnostic yield was significantly greater for Lm\/Ls EVs than for Li EVs (85% vs<\/jats:italic> 55%, P<\/jats:italic>\u2009=\u20090.01). The diagnostic yield was significantly greater for locus superior\/locus medialis EV<\/jats:styled-content>s than for locus inferior EV<\/jats:styled-content>s (85% vs<\/jats:italic> 55%, P<\/jats:italic>\u2009=\u20090.01). GV<\/jats:styled-content>s were found by EGD<\/jats:styled-content> in 29 patients. Only one case was detected by CE<\/jats:styled-content>. PHG<\/jats:styled-content> was found by EGD<\/jats:styled-content> in 35 patients. The diagnostic yield of CE<\/jats:styled-content> for PHG<\/jats:styled-content> was 69% (24\/35). There was no difference in diagnostic yield between cases of severe and mild PHG<\/jats:styled-content> (82% vs<\/jats:italic> 63%, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.44). Diagnostic yield of CE<\/jats:styled-content> for PHG<\/jats:styled-content> in the gastric body was significantly greater than that in the fundus (100% vs<\/jats:italic> 48%, P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.0009).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>CE<\/jats:styled-content> is reliable for diagnosis of F<\/jats:styled-content>2\/F3 and\/or Lm\/Ls EV<\/jats:styled-content>s and of PHG<\/jats:styled-content> in the gastric body.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12372","type":"journal-article","created":{"date-parts":[[2013,8,23]],"date-time":"2013-08-23T11:18:50Z","timestamp":1377256730000},"page":"511-516","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Is small\u2010bowel capsule endoscopy effective for diagnosis of esophagogastric lesions related to portal hypertension?"],"prefix":"10.1111","volume":"29","author":[{"given":"Taiki","family":"Aoyama","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"Oka","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Aikata","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikue","family":"Watari","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriaki","family":"Naeshiro","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeto","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Endoscopy Hiroshima University Hospital Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuaki","family":"Chayama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Graduate School of Biomedical Sciences, Hiroshima University Hiroshima Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(87)90579-8"},{"key":"e_1_2_5_3_1","first-page":"944","article-title":"Portal hypertensive intestinal vasculopathy: a review of the clinical, endoscopic, and histopathologic features","volume":"87","author":"Viggiano TR","year":"1992","journal-title":"Am. 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