{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T14:03:55Z","timestamp":1758809035646},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T00:00:00Z","timestamp":1395273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Multi\u2010detector\u2010row computed tomography (<jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content>) has been reported to be a potentially useful modality for detection of the bleeding origin in patients with acute upper massive gastrointestinal (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>) bleeding. The purpose of this study is to investigate the efficacy of <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> as a routine method for detecting the origin of acute upper <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> bleeding prior to urgent endoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five hundred seventy\u2010seven patients with acute upper <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> bleeding (514 nonvariceal patients, 63 variceal patients) who underwent urgent upper <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> endoscopy were retrospectively analyzed. Patients were divided into three groups: enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content>, unenhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content>, and no <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> before endoscopy. The diagnostic accuracy of <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> for detection of the bleeding origin was evaluated, and the average procedure times needed to endoscopically identify the bleeding origin were compared between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Diagnostic accuracy among endoscopists was 55.3% and 14.7% for the enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> and unenhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> groups, respectively. Among nonvariceal patients, accuracy was 50.2% in the enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> group, which was significantly better than that in the unenhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> group (16.5%). In variceal patients, accuracy was significantly better in the enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> group (96.4%) than in the unenhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> group (0.0%). These accuracies were similar to those achieved by expert radiologists. The average procedure time to endoscopic detection of the bleeding origin in the enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> group was significantly faster than that in the unenhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> and no\u2010<jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Enhanced <jats:styled-content style=\"fixed-case\">MDCT<\/jats:styled-content> preceding urgent endoscopy may be an effective modality for the detection of bleeding origin in patients with acute upper <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> bleeding.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12447","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T02:50:46Z","timestamp":1384397446000},"page":"716-722","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The role of enhanced multi\u2010detector\u2010row computed tomography before urgent endoscopy in acute upper gastrointestinal bleeding"],"prefix":"10.1111","volume":"29","author":[{"given":"Youichi","family":"Miyaoka","sequence":"first","affiliation":[{"name":"Division of Endoscopy Shimane Prefectural Central Hospital  Izumo Shimane Prefecture"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Amano","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Shimane Prefectural Central Hospital  Izumo Shimane Prefecture"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayaka","family":"Ueno","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Izumi","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hironobu","family":"Mikami","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomotaka","family":"Yazaki","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiko","family":"Okimoto","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Sonoyama","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoko","family":"Ito","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Fujishiro","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Shimane Prefectural Central Hospital  Izumo Shimane Prefecture"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naruaki","family":"Kohge","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonori","family":"Imaoka","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Kaken Hospital, International University of Health and Welfare  Ichikawa Chiba Prefecture Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3810\/pgm.1998.06.512"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07517.x"},{"key":"e_1_2_6_4_1","first-page":"236","article-title":"Acute upper gastrointestinal bleeding in the Amsterdam area: incidence, diagnosis, and clinical outcome","volume":"92","author":"Vreeburg EM","year":"1997","journal-title":"Am. 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