{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:18:03Z","timestamp":1760955483786,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2014,8,25]],"date-time":"2014-08-25T00:00:00Z","timestamp":1408924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81270603"],"award-info":[{"award-number":["81270603"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>This study was undertaken to evaluate the clinical characteristics, prognostic factors, and long\u2010term outcomes of patients with mucosa\u2010associated lymphoid tissue (<jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content>) lymphoma in the gastrointestinal (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>) tract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Clinical and pathological features of patients with <jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content> lymphoma in the <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content> tract, who were treated consecutively at <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ianjin <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edical <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ancer <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nstitute and <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital from 2001 to 2011, were evaluated retrospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among a total of 99 identified cases, 79.79% of lymphomas were localized in the stomach, 20.20% in the intestinal tract, and disseminated disease was detected in 35.4% of cases. The estimated 5\u2010year overall survival (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>) and 5\u2010year progression\u2010free survival (<jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content>) rates were 73.1% and 65.1%, respectively. The comparison between stomach and intestinal tract lymphomas demonstrated no significant difference in characteristics, but nodal involvement was significantly lower in gastric <jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content> lymphoma (26.6%) as compared with intestinal tract <jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content> lymphoma (60%, <jats:italic>P<\/jats:italic>\u2009=\u20090.006). The outcomes of gastric and intestinal <jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content> lymphomas were similar (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>, <jats:italic>P<\/jats:italic>\u2009=\u20090.492; <jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content>, <jats:italic>P<\/jats:italic>\u2009=\u20090.408), and so was the survival between proximal and distal gastric lymphomas (<jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>, <jats:italic>P<\/jats:italic>\u2009=\u20090.077; <jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content>, <jats:italic>P<\/jats:italic>\u2009=\u20090.181). Serum lactate dehydrogenase level above normal was identified as the only adverse prognostic factor for both <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PFS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical characteristics and outcomes demonstrated no significant differences between gastric and intestinal tract <jats:styled-content style=\"fixed-case\">MALT<\/jats:styled-content> lymphomas. Serum lactate dehydrogenase level was an independent prognostic factor for the survival of <jats:styled-content style=\"fixed-case\">GI MALT<\/jats:styled-content> lymphoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.12615","type":"journal-article","created":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T12:11:10Z","timestamp":1397477470000},"page":"1678-1684","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of the clinical characteristics and prognostic factors of gastrointestinal mucosa\u2010associated lymphoid tissue (<scp>MALT<\/scp>) lymphoma"],"prefix":"10.1111","volume":"29","author":[{"given":"Xiaoxiao","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Hematology Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center of Cancer Tianjin Key Laboratory of Cancer Prevention and Therapy  Tianjin 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