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Patients with cirrhosis have a high risk of developing acute kidney injury. The clinical characteristics of hepatorenal syndrome (<jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content>) are similar to prerenal uremia, but the condition does not respond to volume expansion. <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> type 1 is rapidly progressive whereas <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> type 2 has a slower course often associated with refractory ascites. A number of factors can precipitate <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> such as infections, alcoholic hepatitis, and bleeding. The monitoring, prevention, early detection, and treatment of <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> are essential. This paper reviews the value of early evaluation of renal function based on two new sets of diagnostic criteria. Interventions for <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> type 1 include terlipressin combined with albumin. In <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> type 2, transjugular intrahepatic portosystemic shunt (<jats:styled-content style=\"fixed-case\">TIPS<\/jats:styled-content>) should be considered. For both types of <jats:styled-content style=\"fixed-case\">HRS<\/jats:styled-content> patients should be evaluated for liver transplantation.<\/jats:p>","DOI":"10.1111\/jgh.12709","type":"journal-article","created":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T02:23:20Z","timestamp":1409106200000},"page":"236-243","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Acute kidney injury and hepatorenal syndrome in cirrhosis"],"prefix":"10.1111","volume":"30","author":[{"given":"Mads","family":"Egerod Israelsen","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Odense University Hospital University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise Lotte","family":"Gluud","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hvidovre University Hospital University of Copenhagen  Hvidovre 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