{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:24:46Z","timestamp":1787243086629,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T00:00:00Z","timestamp":1424649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Shanghai Natural Science Foundation of China","award":["14ZR1406800"],"award-info":[{"award-number":["14ZR1406800"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2015,3]]},"abstract":"Abstract<\/jats:title>\n \n Background and Aim<\/jats:title>\n \n Traditional pathological scoring systems for liver fibrosis progression are predominantly based on the description of architectural changes with no consideration of the amount of collagen fiber deposition. Our purpose was to explore a true histological standard in accordance with the liver stiffness measured by point shear wave elastography (\n PSWE<\/jats:styled-content>\n ) in patients with chronic hepatitis\n B<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A total of 78 patients with liver neoplasms underwent liver stiffness measurements with\n PSWE<\/jats:styled-content>\n as well as biochemical investigations within 3 days before partial hepatectomy. One tissue section of the liver specimens was stained with\n HE<\/jats:styled-content>\n trichrome and evaluated traditionally with the\n S<\/jats:styled-content>\n cheuer scoring system. The other tissue section was stained with picro\n S<\/jats:styled-content>\n irius red and was evaluated according to the semiquantitative\n C<\/jats:styled-content>\n hevallier\n et\u2009al<\/jats:italic>\n . scoring system. In addition, this second tissue section was evaluated for the collagen proportionate area (\n CPA<\/jats:styled-content>\n ) with computer\u2010assisted digital image analysis. The reproducibility of\n PSWE<\/jats:styled-content>\n technology was explored through the intra\u2010class correlation coefficient of a reliability analysis.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The\n PSWE<\/jats:styled-content>\n technology revealed good reproducibility in liver stiffness measurements, and the\n PSWE<\/jats:styled-content>\n values increased with the pathological severity of liver fibrosis on both the\n S<\/jats:styled-content>\n cheuer scoring system and the semiquantitative\n C<\/jats:styled-content>\n hevallier\n et\u2009al<\/jats:italic>\n . scoring system.\n PSWE<\/jats:styled-content>\n values exhibited more reasonable relationships with\n CPA<\/jats:styled-content>\n (\n r<\/jats:italic>\n \u2009=\u20090.628,\n P<\/jats:italic>\n \u2009=\u20090.00\u2009<\u20090.05) than with the\n S<\/jats:styled-content>\n cheuer scoring system (\n r<\/jats:italic>\n \u2009=\u20090.473,\n P<\/jats:italic>\n \u2009=\u20090.00\u2009<\u20090.05) or the\n C<\/jats:styled-content>\n hevallier\n et\u2009al<\/jats:italic>\n . semiquantitative scoring system (\n r<\/jats:italic>\n \u2009=\u20090.487,\n P<\/jats:italic>\n \u2009=\u20090.00\u2009<\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n CPA<\/jats:styled-content>\n is a better pathological parameter than traditional semiquantitative scoring systems in accordance with liver stiffness measured by\n PSWE<\/jats:styled-content>\n technology.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/jgh.12789","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T23:33:41Z","timestamp":1411428821000},"page":"553-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Assessment of liver fibrosis: The relationship between point shear wave elastography and quantitative histological analysis"],"prefix":"10.1111","volume":"30","author":[{"given":"Hong","family":"Ding","sequence":"first","affiliation":[{"name":"Department of Ultrasound Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao\u2010jiao","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010jiao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Pathology Shanghai Medical College Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pathology Shanghai Medical College Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei\u2010jian","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound Zhongshan Hospital Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010yao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Zhongshan Hospital Fudan University Shanghai 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