{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:26:20Z","timestamp":1782847580134,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Provincial natural science research program of higher education institutions of Anhui province","award":["KJ2013A151"],"award-info":[{"award-number":["KJ2013A151"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Upper gastrointestinal endoscopy remains the gold standard for diagnosis of esophageal varices. Trans\u2010abdominal ultrasound, as a noninvasive routine examination for the follow\u2010up of cirrhosis patient, is safe, cheap, easy to perform, and plays an important role. In this study, we attempt to design a practical classification analysis model to predict esophageal varices via ultrasound.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Compared with endoscopy, the ultrasound qualitative signs (lower esophageal Doppler signals, left gastric vein hepatofugal flow, and paraumbilical vein recanalization) and quantitative parameters (spleen diameter, spleen vein diameter, portal vein diameter, and portal vein velocity) have been evaluated in 286 cirrhosis patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The classification analysis model is designed as that: the patients are defined with esophageal varices high risk, who with any ultrasound qualitative signs or who with spleen diameter greater than 162\u2009mm without qualitative parameters. The sensitivity for detecting esophageal varices is 97.5% and the specificity is 82.6%, while the positive predictive value is 96.7%, negative predictive value is 83.4%, and the omission diagnostic rate is 2.5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This classification analysis model design includes ultrasound qualitative signs and spleen diameter, which can be detected easily via routine ultrasound without other auxiliary. The classification analysis model is useful in detecting esophageal varices, which may be a supplement for predicting of esophageal varices, and reducing the frequency of endoscopy in the follow\u2010up of cirrhosis patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.13045","type":"journal-article","created":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T21:04:51Z","timestamp":1437512691000},"page":"194-199","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Predict esophageal varices via routine trans\u2010abdominal ultrasound: A design of classification analysis model"],"prefix":"10.1111","volume":"31","author":[{"given":"Chao\u2010Xue","family":"Zhang","sequence":"first","affiliation":[{"name":"Departments of Ultrasound, The First Affiliated Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian\u2010Ming","family":"Xu","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, The First Affiliated Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia\u2010Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Departments of Infectious disease, The First Affiliated Hospital Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De\u2010Run","family":"Kong","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, The First Affiliated Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Ultrasound, The First Affiliated Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao\u2010Yong","family":"Xu","sequence":"additional","affiliation":[{"name":"Departments of Gastroenterology, The First Affiliated Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Mei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Departments of Infectious disease, The First Affiliated Hospital Anhui Medical University  Hefei Anhui China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,30]]},"reference":[{"issue":"3","key":"e_1_2_6_2_1","first-page":"III1","article-title":"UK guidelines on the management of variceal haemorrhage in cirrhotic patients. 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