{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T19:26:36Z","timestamp":1748978796009},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T00:00:00Z","timestamp":1453939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The aim of this study was to evaluate the validity of the parameters of conventional white\u2010light endoscopy and magnifying endoscopy with narrow\u2010band imaging (MENBI) for the prediction of discrepancies between pre\u2010 and post\u2010resectional histology in cases of gastric adenoma with low\u2010grade dysplasia (LGD) that were diagnosed based on endoscopically biopsied specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of 266 lesions with gastric LGD that were diagnosed by endoscopic forceps biopsies were retrospectively reviewed. The Vienna classification was used for histologic diagnosis. These patients all underwent MENBI examinations followed by analyses of the incidence of histologic discrepancies and histologic heterogeneity. The relationship between white\u2010light endoscopic\/MENBI parameters and the presence of histologic discrepancies was also analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Discrepancies between the pre\u2010 and post\u2010resectional histologies were found in 74 cases (27.9%). Among those cases, the histology was upgraded in 71 cases, whereas the histology was downgraded in three cases. The presence of erythema and positive MENBI findings were independent factors for the prediction of upgraded histologic discrepancies (<jats:italic>P<\/jats:italic>\u2010values\u2009=\u20090.008, &lt;\u20090.001, respectively). A positive MENBI finding yielded the highest predictive value, with a multivariate adjusted odds ratio of 42.46. Histologic heterogeneity in post\u2010resectional specimens was found in 40.8% of cases with upgraded histologic discrepancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>MENBI can provide more accurate information than white\u2010light endoscopy for the prediction of pre\u2010 and post\u2010resectional histologic discrepancies in biopsy\u2010proven gastric LGD. Endoscopic resection is strongly recommended in cases with surface erythema on conventional white\u2010light endoscopy or positive MENBI, irrespective of the lesion size.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.13195","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T19:48:45Z","timestamp":1445024925000},"page":"394-402","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Predicting pre\u2010 and post\u2010resectional histologic discrepancies in gastric low\u2010grade dysplasia: A comparison of white\u2010light and magnifying endoscopy"],"prefix":"10.1111","volume":"31","author":[{"given":"Jin Won","family":"Hwang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Seok","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Seon","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Pathology, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam Ryong","family":"Jee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Heon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Sung","family":"An","sequence":"additional","affiliation":[{"name":"Department of Surgery, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwang Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Beom","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Surgery, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bomi","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology, Busan Paik Hospital Inje University College of Medicine  Busan Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Young","family":"Seol","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Busan Paik Hospital Inje University College of Medicine  Busan Republic of 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