{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T18:27:51Z","timestamp":1783103271195,"version":"3.54.6"},"reference-count":56,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,5,30]],"date-time":"2016-05-30T00:00:00Z","timestamp":1464566400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Celiac disease (CD) is emerging in Asia. While a few population\u2010based studies from Asia have reported a prevalence of CD from 0.1% to 1.3%, the exact prevalence of CD in Asia is not known. We conducted a systematic review and meta\u2010analysis to estimate the prevalence of CD in Asia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>On search of literature, we found 1213 articles, of which 18 articles were included. Diagnosis of CD was based on European Society of Pediatric Gastroenterology, Hepatology and Nutrition guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pooled sero\u2010prevalence of CD in Asia was 1.6% in 47\u2009873 individuals based on positive anti\u2010tissue transglutaminase and\/or anti\u2010endomysial antibodies. Pooled prevalence of biopsy proven CD in Asia was 0.5% in 43\u2009955 individuals. The prevalence of CD among women was higher than in men (0.5% <jats:italic>vs<\/jats:italic> 0.4%, <jats:italic>P<\/jats:italic>\u2009=\u20090.04). The pooled prevalence of CD was 0.3% in Iran, 0.5% in Turkey, 0.6% in India, and 0.7% in Israel. The pooled prevalence of CD was significantly higher in Israel and India as compared with that in Iran.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Celiac disease is not uncommon in Asia, and the sero\u2010prevalence and prevalence of CD in Asia are 1.6% and 0.5%, respectively. The prevalence of CD varies with gender and geographic location. There is a need for population\u2010based prevalence studies in many Asian countries to properly estimate the burden of CD in Asia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.13270","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T06:44:51Z","timestamp":1450421091000},"page":"1095-1101","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":107,"title":["Prevalence of celiac disease in Asia: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"31","author":[{"given":"Prashant","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Medicine Massachusetts General Hospital  Boston USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubhangi","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Medicine Brigham and Women's Hospital  Boston USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor A","family":"Strand","sequence":"additional","affiliation":[{"name":"Medical Services Division Innlandet Hospital Trust  Lillehammer Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Govind K","family":"Makharia","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301346"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071600"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2005.01.006"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2010.23"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/08830185.2011.602443"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1970.tb15545.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.65.8.909"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31821a23d0"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90989-X"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.3.286"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2010.505931"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2001.tb143555.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2000.02290.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124040"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000369537"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000165664.87153.e1"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06606.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.41732"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2009.05932.x"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.15171\/ijhpm.2014.71"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)72172-3"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.15.2008"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.11.014"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.111.092098"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-013-0838-6"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200305000-00003"},{"key":"e_1_2_5_28_1","first-page":"155","article-title":"Prevalence of asymptomatic celiac disease in a Syrian population sample","volume":"6","author":"Challar MH","year":"2004","journal-title":"JABMS"},{"key":"e_1_2_5_29_1","first-page":"415","article-title":"Prevalence of celiac disease in north Indian children","volume":"46","author":"Bhattacharya M","year":"2009","journal-title":"Indian Pediatr."},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.meg.0000224477.51428.32"},{"key":"e_1_2_5_31_1","first-page":"301","article-title":"Prevalence of celiac disease among blood donors in Sistan and Balouchestan Province, Southeastern Iran","volume":"13","author":"Bahari A","year":"2010","journal-title":"Arch. 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