{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:44:28Z","timestamp":1790718268987,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T00:00:00Z","timestamp":1487635200000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>As best estimates on functional gastrointestinal disorders (FGIDs) prevalence are expected from community studies, which are scanty from Asia, we evaluated the prevalence and risk factors of FGIDs in a rural Indian community.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>House\u2010to\u2010house survey was undertaken by trained interviewers using translated\u2010validated Rome III and hospital anxiety and depression questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>Among 3426 subjects\u2009\u2265\u200918\u2009years old from 3 villages in Uttar Pradesh, 84% participated, of whom 80% were finally analyzed. Of these 2774 subjects (age 38.4\u2009\u00b1\u200916.5\u2009years, 1573 [56.7%] male), 2654 [95.7%] were vegetarian and 120 [4.3%] non\u2010vegetarian. Socioeconomic classes were upper (16.7%), upper middle (15.1%), lower middle (22%), upper lower (22.2%), and lower (24%) using Prasad's Classification; 603 (21.7%) had FGIDs (413 [14.9%] dyspepsia, 75 [2.7%] irritable bowel syndrome (IBS) and 115 [4.1%] dyspepsia\u2010IBS overlap), by Rome III criteria. In subjects with dyspepsia, 49\/528 (9%) had epigastric pain, 141 (27%) postprandial distress syndromes (EPS, PDS) and 338 (64%) EPS\u2010PDS overlap. IBS was more often diarrhea than constipation\u2010predominant subtype. On univariate analysis, chewing tobacco, aerated drink, tea\/coffee, disturbed sleep, vegetarianism, and anxiety parameters and presence of dyspepsia predicting occurrence of IBS were associated with FGIDs. On multivariate analysis, chewing tobacco, aerated soft drink, tea\/coffee, vegetarianism, anxiety parameters, and presence of dyspepsia predicting IBS were significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Functional gastrointestinal disorders, particularly dyspepsia\u2010IBS overlap, are common in rural Indian population; the risk factors included chewing tobacco, aerated soft drink, tea\/coffee, vegetarian diet, disturbed sleep, anxiety, and dyspepsia predicting occurrence of IBS.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.13465","type":"journal-article","created":{"date-parts":[[2016,6,5]],"date-time":"2016-06-05T18:46:11Z","timestamp":1465152371000},"page":"378-387","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["Frequency and risk factors of functional gastro\u2010intestinal disorders in a rural Indian population"],"prefix":"10.1111","volume":"32","author":[{"given":"Uday C","family":"Ghoshal","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajan","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical Sciences  Lucknow India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,2,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.03.008"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm14165"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2011.17.1.82"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2005.00627.x"},{"key":"e_1_2_6_6_1","first-page":"22","article-title":"Epidemiological and clinical profile of irritable bowel syndrome in India: report of the Indian Society of Gastroenterology Task Force","volume":"27","author":"Ghoshal UC","year":"2008","journal-title":"Indian J. 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