{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T15:52:37Z","timestamp":1723045957466},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T00:00:00Z","timestamp":1510272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Few studies have shown the associations between colonic diverticula and endoscopic findings such as location, inflammation, number of diverticula, sigmoid colon rigidity, and bowel habits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Japanese subjects who underwent total colonoscopies at six centers in Japan from November 2015 to October 2016 were analyzed. Bowel habits were evaluated using the Gastrointestinal Symptom Rating Scale. Location and number of diverticula, inflammation, and sigmoid colon rigidity were evaluated from endoscopy results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 762 subjects (486 men and 276 women [ratio, 1.76:1]) whose mean age was 65.5\u00a0\u00b1\u00a011.4\u00a0years were evaluated. In multivariate analysis, presence of constipation was associated with a significantly lower likelihood of left\u2010sided colonic diverticula (odds ratio\u00a0=\u00a00.40, 95% confidence interval 0.20\u20130.82, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.012), whereas right\u2010sided and bilateral\u2010sided colonic diverticula, multiple colonic diverticula, inflammation findings, and sigmoid colon rigidity were not related to bowel habits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among endoscopic findings related to colonic diverticula and bowel habits, only left\u2010sided colonic diverticula were inversely associated with constipation, whereas inflammation findings, multiple diverticula, and sigmoid colon rigidity were not related to bowel habits. However, the association of inflammation findings with colonic diverticula and bowel habits should be further studied. Investigation of changes in left\u2010sided colonic diverticula may lead to new treatments for constipation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.13805","type":"journal-article","created":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T03:18:51Z","timestamp":1492658331000},"page":"1938-1942","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between endoscopic findings related to colonic diverticula and bowel habits: A multicenter study in Japan"],"prefix":"10.1111","volume":"32","author":[{"given":"Eiji","family":"Yamada","sequence":"first","affiliation":[{"name":"Gastroenterology Division Saiseikai Yokohama\u2010shi Nanbu Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Kuriyama","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Chigasaki Municipal Hospital  Chigasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eri","family":"Uchida","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Chigasaki Municipal Hospital  Chigasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoriko","family":"Murata","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Chigasaki Municipal Hospital  Chigasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Hata","sequence":"additional","affiliation":[{"name":"Gastroenterology Division Chigasaki Municipal Hospital  Chigasaki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataka","family":"Tagri","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology Yokohama City University School of Medicine  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Isozaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Matsushita Memorial Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Oyamada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Matsushita Memorial Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Surgery Miura City Hospital  Miura Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takafumi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Keiyu Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Mizuki","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Keiyu Hospital  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Inamori","sequence":"additional","affiliation":[{"name":"Department of Medical Education Yokohama City University School of Medicine  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriaki","family":"Manabe","sequence":"additional","affiliation":[{"name":"Division of Endoscopy and Ultrasonography Kawasaki Medical School  Kurashiki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Haruma","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Kawasaki Medical School  Kurashiki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Yokohama City University School of Medicine  Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.32978"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000089779"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/795241"},{"key":"e_1_2_6_5_1","first-page":"367","article-title":"Diverticulosis of the colon","volume":"137","author":"Havia T","year":"1971","journal-title":"Acta Chir. 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