{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:20:50Z","timestamp":1762507250468,"version":"3.37.3"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T00:00:00Z","timestamp":1519603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703274"],"award-info":[{"award-number":["81703274"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The association between <jats:styled-content style=\"fixed-case\"><jats:italic>Helicobacter pylori<\/jats:italic><\/jats:styled-content> (<jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content>) and gallbladder diseases is still unclear and is controversial. We conducted a retrospective study to clarify the prevalence of gallbladder diseases and factors related to gallbladder diseases and relationships between <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> infection, gallstones, cholecystitis, and cholecystic polypus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The retrospective study was performed at the Aerospace Center Hospital in Beijing. The subjects in this study were a healthy population who underwent health examinations at the hospital between 2012 and 2015. The logistic regression models were used to explore the relationships between <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> infection and gallbladder diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 7803 (43.4%) subjects with <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> infection, 995 (5.5%) with gallstones, 219 (1.2%) with cholecystitis, and 1003 (5.6%) with cholecystic polypus amongst 17\u00a0971 subjects, respectively. In subjects aged 45\u00a0years or less, the prevalence of gallstones in the <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> (+) group was lower than that in the <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> (\u2212) group (odds ratio\u00a0=\u00a00.653; 95% confidence interval: 0.468\u20130.911; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.012). The prevalence of cholecystic polypus in the <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> (+) group was significantly higher than that in the <jats:styled-content style=\"fixed-case\"><jats:italic>H.\u00a0pylori<\/jats:italic><\/jats:styled-content> (\u2212) group (odds ratio\u00a0=\u00a01.160; 95% confidence interval: 1.012\u20131.328; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.033).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\"><jats:italic>Helicobacter pylori<\/jats:italic><\/jats:styled-content> infection was related with cholecystic polypus and gallstones in a Chinese population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.14054","type":"journal-article","created":{"date-parts":[[2017,11,27]],"date-time":"2017-11-27T12:34:56Z","timestamp":1511786096000},"page":"1207-1212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Association between <scp><i>Helicobacter pylori<\/i><\/scp> infection and gallbladder diseases: A retrospective study"],"prefix":"10.1111","volume":"33","author":[{"given":"Mei\u2010Yan","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Nutrition Aerospace Center Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010Hui","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Laboratorial Science and Technology School of Public Health Peking University  Beijing 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