{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T18:29:13Z","timestamp":1775500153574,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T00:00:00Z","timestamp":1520553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Polypoid lesions of the gallbladder may be neoplastic or non\u2010neoplastic. Correct diagnosis would help reduce unnecessary cholecystectomies. This study aimed to determine the predictive value of individual ultrasound characteristics for diagnosis of neoplastic polyps and to build a scoring system based on these characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 109 patients with gallbladder polyps \u2265\u00a06\u00a0mm underwent conventional ultrasound examination and received finally diagnosis by pathological examination. All images were analyzed to determine characteristics of the lesions. Univariate and multivariate analyses were used to identify the predictors of neoplastic polyps, and a scoring system was built based on multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Maximum diameter, height\/width ratio, base width, presence of hyper\u2010echoic spots, and intralesional blood flow were statistically significant (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.011, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.016, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.003, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.031, and <jats:italic>P<\/jats:italic>\u00a0=\u00a00.022, respectively) predictors of neoplastic lesions. The total score\u00a0=\u00a0(Maximum diameter, \u2265\u00a013.9\u00a0mm\u00a0=\u00a01, &lt;\u00a013.9\u00a0=\u00a00)\u00a0+\u00a0(Base width, \u2265\u00a03.5\u00a0mm\u00a0=\u00a01, &lt;\u00a03.4\u00a0=\u00a00)\u00a0+\u00a0(Height\/width ratio, \u2264\u00a01.05\u00a0=\u00a01, &gt;\u00a01.05\u00a0=\u00a00)\u00a0+\u00a0(Hyper\u2010echoic spots, presence\u00a0=\u00a00, absence\u00a0=\u00a01)\u00a0+\u00a0(Blood flow, presence\u00a0=\u00a01, absence\u00a0=\u00a00). Receiver operating characteristic curve showed that the sensitivity, specificity, and accuracy for the risk of neoplastic polyps with scores of 3 or higher were 81.6%, 86.7%, and 84.4%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This ultrasound\u2010based scoring system could be a useful means for differentiating between neoplastic and non\u2010neoplastic gallbladder polyps in the clinic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.14080","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T09:32:43Z","timestamp":1514367163000},"page":"1295-1299","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Ultrasound\u2010based scoring system for differential diagnosis of polypoid lesions of the gallbladder"],"prefix":"10.1111","volume":"33","author":[{"given":"Xue\u2010Song","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Ultrasound, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biliary and Pancreatic Surgery, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Hong","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Fen","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun\u2010Yang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Biliary and Pancreatic Surgery, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng\u2010Hua","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biliary and Pancreatic Surgery, Renji Hospital, School of Medicine Shanghai Jiaotong University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,9]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.01.011"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05769.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-013-3033-1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i28.4526"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-011-1696-2"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048371"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.34.6.1061"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.3233\/CH-121651"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-35859"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.196.2.7617866"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.46.2.250"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110313251816"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0104-42302010000300017"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-3146-7"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v17.i17.2216"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-008-0725-2"},{"key":"e_1_2_5_18_1","first-page":"97","article-title":"Factors associated with malignancy in gallbladder polyps without gallbladder stone","volume":"52","author":"Lee JS","year":"2008","journal-title":"Korean J. 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