{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T10:46:07Z","timestamp":1780742767993,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T00:00:00Z","timestamp":1542758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Few studies compared endoscopic ultrasound (EUS)\u2010guided fine needle aspiration (EUS\u2010FNA) with endoscopic retrograde cholangiopancreatography (ERCP)\u2010based tissue sampling in terms of diagnostic accuracy in suspected malignant biliary obstruction. We evaluated and compared the diagnostic performance of EUS\u2010FNA and ERCP\u2010based tissue sampling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter study included 263 patients with suspected malignant biliary obstruction who underwent same\u2010session EUS and ERCP between 2012 and 2016.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Malignancies were confirmed in 239 patients (90.9%) and benign in 24 patients (9.1%). Overall diagnostic sensitivity and accuracy were 73.6% and 76.1% for EUS\u2010FNA, 56.5% and 60.5% for ERCP, and 85.8% and 87.1% for EUS\/ERCP combination. EUS\u2010FNA showed higher overall performances compared with ERCP (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), whereas EUS\/ERCP combination was superior to EUS\u2010FNA alone (<jats:italic>P<\/jats:italic>\u2010value\u00a0&lt;\u00a00.001). EUS\u2010FNA showed higher sensitivity and accuracy compared with ERCP for pancreatic masses (<jats:italic>n<\/jats:italic>\u00a0=\u00a0187, both <jats:italic>P<\/jats:italic>\u2010values\u00a0&lt;\u00a00.001) but not for biliary lesions (<jats:italic>n<\/jats:italic>\u00a0=\u00a076, both <jats:italic>P<\/jats:italic>\u2010values\u00a0=\u00a00.847). Sensitivity and accuracy of EUS\/ERCP combination were superior to those of EUS\u2010FNA for both pancreatic and biliary lesions (both <jats:italic>P<\/jats:italic>\u2010values\u00a0&lt;\u00a00.001). For patients with large mass (\u2265\u00a04\u00a0cm), there was no significant differences between ERCP\/EUS combination and EUS\u2010FNA (<jats:italic>P<\/jats:italic>\u2010value\u00a0=\u00a00.31).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Same\u2010session EUS\u2010FNA and ERCP combination was superior to EUS\u2010FNA for both pancreatic masses and biliary lesions. Same\u2010session EUS\/ERCP combination can be considered a proper diagnostic method for suspected malignant biliary obstruction regardless of the origin of lesions. On the other hand, EUS\u2010FNA alone was sufficient for diagnosis compared with EUS\/ERCP combination in cases with large mass. Strategic diagnostic approach, according to clinical features of individual patient, is required.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.14528","type":"journal-article","created":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T02:48:06Z","timestamp":1540954086000},"page":"799-805","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Same\u2010session endoscopic ultrasound\u2010guided fine needle aspiration and endoscopic retrograde cholangiopancreatography\u2010based tissue sampling in suspected malignant biliary obstruction: A multicenter experience"],"prefix":"10.1111","volume":"34","author":[{"given":"Jung Hyun","family":"Jo","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Min","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, Kyungpook National University Kyungpook National University Chilgok Hospital  Daegu Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hyuck","family":"Jun","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon Jae","family":"Chung","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Hyeon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Wonkwang University Hospital  Iksan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Wan","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0693-1415","authenticated-orcid":false,"given":"Jaihwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul National University Bundang Hospital Seoul National University College of Medicine  Seongnam Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Research Group for 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