{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:12:15Z","timestamp":1787015535921,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,1,15]],"date-time":"2019-01-15T00:00:00Z","timestamp":1547510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100011645","name":"Kaohsiung Medical University Chung-Ho Memorial Hospital","doi-asserted-by":"publisher","award":["KMUH97\u20107G44"],"award-info":[{"award-number":["KMUH97\u20107G44"]}],"id":[{"id":"10.13039\/501100011645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["M094002"],"award-info":[{"award-number":["M094002"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSC\u201091\u20102315\u2010B\u2010037\u2010002"],"award-info":[{"award-number":["NSC\u201091\u20102315\u2010B\u2010037\u2010002"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSC NSC\u201092\u20102314\u2010B037\u2010045"],"award-info":[{"award-number":["NSC NSC\u201092\u20102314\u2010B037\u2010045"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Asian populations have relatively lower prevalence of gastroesophageal reflux disease and tend to exhibit symptoms of prolonged gastric retention. However, it remains unknown if slower gastric emptying influences its features in Asian countries. We prospectively assessed the potential implications of slower gastric emptying in an Asian\u2010Pacific cohort of gastroesophageal reflux disease by a hospital\u2010based survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      One hundred fifty\u2010two patients of gastroesophageal reflux disease complete the scintigraphic measurement of solid phase of gastric emptying. Clinical symptoms and psychological stress are recorded by self\u2010report questionnaire. The status of\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      infection, blood level of pepsinogen I, and I\/II ratio are assessed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010seven percent and 28% of the patients have slower gastric emptying rate, depending on the incremental defined cut\u2010off values of slower gastric emptying, respectively. Multiple logistic regression analysis indicates that older age and depression score are independently related to slower gastric emptying. Subgroup analysis discloses that patients with slower gastric emptying and higher depression score tend to present with non\u2010erosive esophagitis whereas higher body mass index level and male gender in patients with normal gastric emptying predict the presence of erosive reflux disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our study cohort of Asian patients indicates distinctive clinical implications of slower gastric emptying in patients with gastroesophageal reflux disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.14572","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T20:12:54Z","timestamp":1544818374000},"page":"837-842","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Predictor of slower gastric emptying in gastroesophageal reflux disease: Survey of an Asian\u2010Pacific cohort"],"prefix":"10.1111","volume":"34","author":[{"given":"Kuan\u2010Yuan","family":"Wang","sequence":"first","affiliation":[{"name":"Division of Geriatrics and Gerontology, Department of Internal Medicine Kaohsiung Medical University Hospital  Kaohsiung Taiwan"},{"name":"Department of Internal Medicine Kaohsiung Municipal Cijin Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Wen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsu\u2010Nai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Public Health, College of Health Science Kaohsiung Medical University  Kaohsiung 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Gastroenterology, Department of Internal Medicine Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huang\u2010Ming","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Department of Internal Medicine Kaohsiung Municipal Ta\u2010Tung Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeng\u2010Yih","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine Kaohsiung Medical University  Kaohsiung Taiwan"},{"name":"Division of Gastroenterology, Department of Internal Medicine Kaohsiung Medical University Hospital  Kaohsiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao\u2010Hung","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine 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