{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T10:41:06Z","timestamp":1772707266256,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,1,16]],"date-time":"2020-01-16T00:00:00Z","timestamp":1579132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>This aims to study incidence of re\u2010bleeding on anticoagulation and survival of Budd\u2013Chiari syndrome (BCS) patients presenting with variceal bleeding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Budd\u2013Chiari syndrome patients presenting with variceal bleed between 01\/01\/2007 and 01\/05\/2019 were retrospectively studied. Patients underwent endoscopic treatment\u00a0\u00b1\u00a0endovascular therapy, followed by anticoagulation. Variceal re\u2010bleed (on anticoagulation) and survival were studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 376 BCS patients diagnosed during the study period, 40 (10.7%) patients, presenting with variceal bleed (age 33 [25\u201340] years; male patients 70%; Rotterdam score 1.13 [0.63\u20131.22]), Group 1 were compared with 40 randomly selected age\u2010matched BCS patients presenting with ascites, no bleeds (40 [23\u201342] years; male patients 42.5%; Rotterdam score 1.11 [1.09\u20131.16]), Group 2. The commonest site of obstruction was hepatic vein (65%) in Group 1 and combined hepatic veins and inferior vena cava (57.5%) in Group 2 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). Thirty\u2010six Group 1 patients underwent endoscopic intervention (variceal ligation, 33; sclerotherapy, 2; glue injection, 1). Endovascular intervention was performed in 30 Group 1 patients (angioplasty\u00a0\u00b1\u00a0stent, 22; endovascular shunt, 8) and in 34 Group 2 patients (angioplasty\u00a0\u00b1\u00a0stent, 26; endovascular shunt, 8). All 80 patients were started on anticoagulation. Variceal bleed on anticoagulation occurred in five patients in Group 1 and three patients in Group 2. One\u2010year and 5\u2010year survival were 94.2% and 87.5%, respectively, in Group 1 and 100% and 80%, respectively, in Group 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>About one\u2010tenth of BCS patients present with variceal bleed. On management with endoscopic\u00a0\u00b1\u00a0endovascular therapy, followed by anticoagulation, variceal re\u2010bleed in these patients were comparable with those in BCS patients presenting with ascites and survival was excellent at 1 and 5\u00a0years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.14971","type":"journal-article","created":{"date-parts":[[2020,1,4]],"date-time":"2020-01-04T06:15:10Z","timestamp":1578118510000},"page":"1397-1403","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Anticoagulating Budd\u2013Chiari syndrome patients presenting with variceal bleed: A retrospective study"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9841-8768","authenticated-orcid":false,"given":"Anand","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Hepatology Christian Medical College  Vellore 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