{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T00:43:56Z","timestamp":1776300236739,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>There are few cases of duodenal mucosa\u2010associated lymphoid tissue (MALT) lymphoma reported in the literature, and little is known about the clinical course of this disease. Here, we aimed to characterize the clinical features of duodenal MALT lymphoma by comparison with gastric MALT lymphoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirteen patients diagnosed with duodenal MALT lymphoma at Asan Medical Center from March 1997 to February 2017 were included in this retrospective study, along with patients with gastric MALT lymphoma, matched by age and sex at a 1:10 ratio.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median age of patients with duodenal MALT lymphoma was 49 (range 20\u201372) years, and 53.8% (7\/13) were male. Comparison of patient characteristics indicated that <jats:italic>Helicobacter pylori<\/jats:italic> infection (46.2% <jats:italic>vs<\/jats:italic> 90.8%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and lymph node metastasis (23.1% <jats:italic>vs<\/jats:italic> 5.4%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.049) rates differed between patients with duodenal and gastric MALT lymphoma. Overall complete remission (61.5% <jats:italic>vs<\/jats:italic> 86.2%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.021) and complete remission after initial <jats:italic>H.\u00a0pylori<\/jats:italic> eradication therapy (50% <jats:italic>vs<\/jats:italic> 87.7%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.037) were significantly lower in patients with duodenal than gastric MALT lymphoma. Complications including bleeding, stricture, and transformation to high\u2010grade lymphoma occurred in a total of seven patients (4.9%), with a higher incidence in patients with duodenal than gastric MALT lymphoma (38.5% <jats:italic>vs<\/jats:italic> 1.5%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Duodenal MALT lymphoma is very rare, and treatment outcomes appear to be inferior to those of gastric MALT lymphoma.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.15157","type":"journal-article","created":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T05:20:13Z","timestamp":1592889613000},"page":"406-412","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Clinical course of duodenal mucosa\u2010associated lymphoid tissue lymphoma: Comparison with gastric mucosa\u2010associated lymphoid tissue lymphoma"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6764-9099","authenticated-orcid":false,"given":"Hee Kyong","family":"Na","sequence":"first","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hyun","family":"Won","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0030-3744","authenticated-orcid":false,"given":"Ji Yong","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ga Hee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3771-3691","authenticated-orcid":false,"given":"Kee Wook","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4250-4683","authenticated-orcid":false,"given":"Do Hoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kee Don","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3195-8794","authenticated-orcid":false,"given":"Ho June","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gin Hyug","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1281-5859","authenticated-orcid":false,"given":"Hwoon\u2010Yong","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwa Jung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics University of Ulsan College of Medicine, Asan Medical Center  Seoul 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