{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:15:11Z","timestamp":1787062511538,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,8,6]],"date-time":"2020-08-06T00:00:00Z","timestamp":1596672000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Endoscopic resection for early gastric cancer (EGC) is widely performed. However, there is still a paucity of strong evidence regarding long\u2010term outcomes after endoscopic submucosal dissection (ESD) for the expanded indication criteria of the Japanese guidelines (ver. 2010).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Endoscopic submucosal dissection was performed in patients with EGC that met the expanded indication criteria: (i) cT1a, differentiated\u2010type EGC of 2 to 5\u00a0cm, ulcer negative or (ii) cT1a, differentiated\u2010type EGC of \u22643\u00a0cm, ulcer positive. Patients whose pathological examination fulfilled the curative resection criteria were then enrolled in this cohort study: negative vertical margin, negative lymphovascular invasion, and (i) pT1a, differentiated\u2010type, and ulcer negative; (ii) pT1a, differentiated\u2010type, \u22643\u00a0cm, and ulcer positive; or (iii) pT1b1 (&lt;500\u2010\u03bcm submucosal invasion), differentiated\u2010type, and \u22643\u00a0cm. Patients with only a positive horizontal margin as a noncurative factor were included for follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From September 2003 to February 2012, a total of 356 patients underwent ESD, and 214 were enrolled in the survival analysis. One hundred twenty patients (56%) had &gt;2\u00a0cm in diameter and ulcer\u2010negative lesions, and 94 (44%) had \u22643\u00a0cm and ulcer\u2010positive lesions. The vital status at 5\u00a0years after ESD was confirmed in all (100%) patients. No local or metastatic recurrence was detected; however, 26 metachronous gastric cancers developed, and 1 patient died of metachronous gastric cancer. The 5\u2010year disease\u2010specific and overall survival rates were 99.5% (95% confidence interval [CI], 97.2%\u2013100%) and 93.9% (95% CI, 89.8%\u201396.4%), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ESD for EGC that fulfills the expanded criteria is feasible and shows favorable long\u2010term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.15182","type":"journal-article","created":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T15:21:03Z","timestamp":1594740063000},"page":"664-670","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Long\u2010term outcomes after endoscopic submucosal dissection for differentiated\u2010type early gastric cancer that fulfilled expanded indication criteria: A prospective cohort study"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5750-0976","authenticated-orcid":false,"given":"Satoki","family":"Shichijo","sequence":"first","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriya","family":"Uedo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kanesaka","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ohta","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Kansai Rosai Hospital  Amagasaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusaku","family":"Shimamoto","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayasu","family":"Ohmori","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masamichi","family":"Arao","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7721-8292","authenticated-orcid":false,"given":"Taro","family":"Iwatsubo","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6183-2439","authenticated-orcid":false,"given":"Sho","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenshi","family":"Matsuno","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyoshi","family":"Iwagami","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuntaro","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Matsuura","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Maekawa","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2264-2963","authenticated-orcid":false,"given":"Hiroko","family":"Nakahira","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachiko","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3814-298X","authenticated-orcid":false,"given":"Yoji","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Higashino","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryu","family":"Ishihara","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Fukui","sequence":"additional","affiliation":[{"name":"Center for Cancer Control and Statistics Osaka International Cancer Institute  Osaka Japan"},{"name":"Department of Medical Statistics, Research &amp; Development Center Osaka Medical College  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuri","family":"Ito","sequence":"additional","affiliation":[{"name":"Center for Cancer Control and Statistics Osaka International Cancer Institute  Osaka Japan"},{"name":"Department of Medical Statistics, Research &amp; Development Center Osaka Medical College  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Narahara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hyogo Prefectural Nishinomiya Hospital  Nishinomiya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Ishiguro","sequence":"additional","affiliation":[{"name":"Pathology Pathology and Cytology Laboratories, Inc  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyasu","family":"Iishi","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Oncology Osaka International Cancer Institute  Osaka Japan"},{"name":"Department of Gastroenterology Itami City Hospital  Itami Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-005-0357-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1215129"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31822f3988"},{"key":"e_1_2_6_6_1","first-page":"66","article-title":"Long\u2010term survival after endoscopic resection for early gastric cancer in the remnant stomach: comparison with radical surgery","volume":"28","author":"Yamashina T","year":"2015","journal-title":"Ann. Gastroenterol."},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.03.1059"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011720"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-011-0042-4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-015-0469-0"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.06.049"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2011.04.038"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1392249"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7033"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12099"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-017-0704-y"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-018-0414-3"},{"key":"e_1_2_6_18_1","unstructured":"SEER program coding and staging manual 2004 revision 1. Cited 20 Jun2020. Available from URL:https:\/\/seer.cancer.gov\/archive\/manuals\/2004Revision1\/SPM_2004_maindoc.r1.pdf"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011681"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-011-0041-5"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1344332"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-013-0325-z"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2012.02254.x"},{"key":"e_1_2_6_24_1","first-page":"101","article-title":"The relative survival rate: a statistical methodology","volume":"6","author":"Ederer F","year":"1961","journal-title":"Natl. Cancer Inst. Monogr."},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2015.10.039"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-122379"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-018-6451-2"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.02.015"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-009-0137-4"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.09.027"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v5.i6.281"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1443-1661.2012.01376.x"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255932"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2016.06.033"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01197.x"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301647"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2010.06442.x"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/950734"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1392484"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12146"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61159-9"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.01.028"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.15182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.15182","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgh.15182","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.15182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T05:13:54Z","timestamp":1693545234000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.15182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,6]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/jgh.15182"],"URL":"https:\/\/doi.org\/10.1111\/jgh.15182","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,6]]},"assertion":[{"value":"2019-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}