{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:12:05Z","timestamp":1791526325819,"version":"4.3.4"},"reference-count":75,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T00:00:00Z","timestamp":1595980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Inflammatory bowel disease (IBD) has increased in incidence and prevalence in Asian countries since the end of the 20th century. Moreover, differences in the cause, phenotypes, and natural history of IBD between the East and West have been recognized. Therefore, the Asian Organization for Crohn's and Colitis and the Asia Pacific Association of Gastroenterology have established recommendations on medical management of IBD in Asia. Initially, the committee members drafted 40 recommendations, which were then assessed according to Grading of Recommendations Assessment, Development and Evaluation. Eight statements were rejected as this indicated that consensus had not been reached. The recommendations encompass pretreatment evaluation; medical management of active IBD; medical management of IBD in remission; management of IBD during the periconception period and pregnancy; surveillance strategies for colitis\u2010associated cancer; monitoring side effects of thiopurines and methotrexate; and infections in IBD.<\/jats:p>","DOI":"10.1111\/jgh.15185","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T11:57:09Z","timestamp":1594900629000},"page":"637-645","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology practice recommendations for medical management and monitoring of inflammatory bowel disease in Asia"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6388-6206","authenticated-orcid":false,"given":"Zhihua","family":"Ran","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Renji Hospital, School of Medicine Shanghai Jiao Tong University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaichun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fourth Military Medical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyoshi","family":"Matsuoka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Toho University Sakura Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon Tae","family":"Jeen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu Chen","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, National Taiwan University Hospital National Taiwan University College of Medicine  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1577-0118","authenticated-orcid":false,"given":"Vineet","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minhu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin\u2010Jin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The Sixth Affiliated Hospital, Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8533-2669","authenticated-orcid":false,"given":"Akira","family":"Andoh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University  Otsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Jong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kyung Hee University School of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2772-2575","authenticated-orcid":false,"given":"Suk\u2010Kyun","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Asan Medical Center University of Ulsan College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoru","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siew Chien","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Medicine and Therapeutics, Institute of Digestive Disease, LKS Institute of Health Science, State Key Laboratory of Digestive Disease The Chinese University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshifumi","family":"Hibi","sequence":"additional","affiliation":[{"name":"Center for Advanced IBD Research and Treatment Kitasato University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida Normiha","family":"Hilmi","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Malaya  Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Toho University  Sakura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Soo","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Hanyang University Guri Hospital  Guri Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai Keung","family":"Leung","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Medicine University of Hong Kong  Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Sollano","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Santo Tomas  Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choon Jin","family":"Ooi","sequence":"additional","affiliation":[{"name":"Gleneagles Medical Centre and Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaming","family":"Qian","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2016.14.2.111"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000446625"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3060"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx009"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx008"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw169"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw168"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000152"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i34.6306"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12324"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13840"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13851"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1751-2980.12437"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2010.01751.x"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201608-647OC"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2012.01643.x"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V100.2.391"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23190"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-314918"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.28676"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.10.025"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.10.011"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(08)62312-4"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198712243172603"},{"key":"e_1_2_12_26_1","first-page":"CD000543","article-title":"Oral 5\u2010aminosalicylic acid for induction of remission in ulcerative colitis","volume":"4","author":"Wang Y","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.060103"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.09.033"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199710093371502"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.030"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.03.003"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0904492"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000001203"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2014.07.003"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.10.052"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2003.50145"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00238-1"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.09.033"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(01)00022-X"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(05)70063-7"},{"key":"e_1_2_12_41_1","first-page":"CD000542","article-title":"Enteral nutritional therapy for induction of remission in Crohn's disease","volume":"4","author":"Narula N","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-346304"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01247.x"},{"key":"e_1_2_12_44_1","first-page":"CD000544","article-title":"Oral 5\u2010aminosalicylic acid for maintenance of remission in ulcerative colitis","volume":"5","author":"Wang Y","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.890567"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5119.387"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(65)90973-6"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.39.1.82"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8536887"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1998.00285.x"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.4.493"},{"key":"e_1_2_12_52_1","first-page":"CD000067","article-title":"Azathioprine or 6\u2010mercaptopurine for maintenance of remission in Crohn's disease","volume":"2015","author":"Chande N","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_12_53_1","first-page":"678","article-title":"Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding)","volume":"27","author":"Martinez Lopez JA","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9926(200012)62:6<385::AID-TERA5>3.0.CO;2-Z"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000092"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01756.x"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.10.024"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12833"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/153.10.961"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(17)30004-3"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.00287.x"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000117"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.143453"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2019.04.219"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.08.002"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.11.025"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2013.06.006"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e318281f28f"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000589"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2017.01.162"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0639-6"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2004.05.013"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2006.00869.x"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03620.x"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365520500408584"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13796"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjgh.15185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.15185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgh.15185","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.15185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T05:15:07Z","timestamp":1693545307000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.15185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,29]]},"references-count":75,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/jgh.15185"],"URL":"https:\/\/doi.org\/10.1111\/jgh.15185","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,29]]},"assertion":[{"value":"2019-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}