{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T08:08:20Z","timestamp":1789632500302,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,10,14]],"date-time":"2020-10-14T00:00:00Z","timestamp":1602633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Most patients with gastric tumors and precancerous lesions are asymptomatic, which often results in delayed diagnosis and treatment. Compared with conventional gastroscopy and capsule endoscopy, magnetic\u2010controlled capsule endoscopy is a non\u2010invasive, effective, and cost\u2010efficient diagnostic modality for gastric examination. We retrospectively investigated magnetic\u2010controlled capsule endoscopy as a screening tool for gastrointestinal lesions (particularly gastric tumors and precancerous lesions) in asymptomatic individuals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective study, 1757 patients who voluntarily underwent magnetic\u2010controlled capsule endoscopy between January and December 2019 at nine medical centers across Shaanxi province based on strict inclusion and exclusion criteria were enrolled. The primary outcomes were gastric tumor and precancerous lesion detection rates and procedural safety.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The upper and lower gastrointestinal lesion detection rates were 98.35% (1728\/1757) and 21.61% (78\/361), respectively; 2.28% of patients were diagnosed with gastric tumors including gastric cancer (4\/1757) and submucosal tumors (36\/1757). Three types of precancerous lesions were found in 591 patients (33.64%), including chronic atrophic gastritis (23.16%), gastric polyp (10.98%), and gastric ulcer (2.96%). For patients aged over 40\u00a0years, the detection rate of precancerous lesions was higher (14.36% <jats:italic>vs<\/jats:italic> 42.58%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). No patient was diagnosed with small intestinal cancer. No adverse events occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Magnetic\u2010controlled capsule endoscopy could be used as a promising novel screening modality for diagnosis of gastrointestinal lesions in asymptomatic individuals, specifically gastric tumors and precancerous lesions, with the advantages of safety, non\u2010invasiveness, effectiveness, and cost\u2010efficiency.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.15282","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T03:55:34Z","timestamp":1601524534000},"page":"1267-1275","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Screening value for gastrointestinal lesions of magnetic\u2010controlled capsule endoscopy in asymptomatic individuals"],"prefix":"10.1111","volume":"36","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudan","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yarui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangli","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinlan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuixiang","family":"He","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9142-2900","authenticated-orcid":false,"given":"Guifang","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Xi'an Jiaotong University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21338"},{"key":"e_1_2_6_4_1","first-page":"408","article-title":"Consensus on screening and endoscopic diagnosis and treatment early of early gastric cancer in China","volume":"19","author":"Liao Z","year":"2014","journal-title":"Chinese J. 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