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Rebleeding is a significant clinical outcome of CDB, but there is no cumulative evidence comparing reduction of short\u2010term and long\u2010term rebleeding between them. Thus, we conducted a systematic review and meta\u2010analysis to determine which endoscopic treatment is more effective to reduce recurrence of CDB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive search of the databases PubMed\/MEDLINE and Embase was performed through December 2019. Main outcomes were early and late rebleeding rates, defined as bleeding within 30\u00a0days and 1\u00a0year of endoscopic therapy for CDB. Initial hemostasis, need for transcatheter arterial embolization, or surgery were also assessed. Overall pooled estimates were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixteen studies fulfilled the eligibility criteria, and a total of 790 participants were included. The pooled prevalence of early rebleeding was significantly lower for band ligation than clipping (0.08 <jats:italic>vs<\/jats:italic> 0.19; heterogeneity test, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.012). The pooled prevalence of late rebleeding was significantly lower for band ligation than clipping (0.09 <jats:italic>vs<\/jats:italic> 0.29; heterogeneity test, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.024). No significant difference of initial hemostasis rate was noted between the two groups. Pooled prevalence of need for transcatheter arterial embolization or surgery was significantly lower for band ligation than clipping (0.01 <jats:italic>vs<\/jats:italic> 0.02; heterogeneity test, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.031). There were two cases with colonic diverticulitis due to band ligation but none in clipping.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Band ligation therapy was more effective compared with clipping to reduce recurrence of colonic diverticular hemorrhage over short\u2010term and long\u2010term durations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.15370","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T05:29:24Z","timestamp":1607578164000},"page":"1738-1743","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Cumulative evidence for reducing recurrence of colonic diverticular bleeding using endoscopic clipping <i>versus<\/i> band ligation: Systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7255-4024","authenticated-orcid":false,"given":"Naoyoshi","family":"Nagata","sequence":"first","affiliation":[{"name":"Department of Gastroenterological Endoscopy Tokyo Medical University  Tokyo Japan"},{"name":"Department of Gastroenterology and Hepatology National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5047-6195","authenticated-orcid":false,"given":"Ryota","family":"Niikura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Tokyo Shinagawa Hospital  Tokyo 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