{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T17:26:19Z","timestamp":1785000379505,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We had previously reported that the administration of Gastrografin through a nasogastric tube (NGT\u2010G) followed by long tube (LT) strategy could be a novel standard treatment for adhesive small bowel obstruction (ASBO); however, the long\u2010term outcomes after initial improvement remain unknown. This study aimed to analyze the long\u2010term outcomes of first\u2010line NGT\u2010G.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Enrolled patients with ASBO were randomly assigned to receive LT or NGT\u2010G between July 2016 and November 2018. Thereafter, the cumulative surgery rate, cumulative recurrence rate, and overall survival (OS) rate were analyzed. In addition, subset analysis was conducted to determine the cumulative recurrence rate according to colonic contrast with Gastrografin at 24\u00a0h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 223 patients (LT group, <jats:italic>n<\/jats:italic>\u00a0=\u00a0111; NGT\u2010G group, <jats:italic>n<\/jats:italic>\u00a0=\u00a0112) were analyzed over a median follow\u2010up duration of 550\u00a0days. The cumulative 1\u2010year surgery rates, cumulative 1\u2010year recurrence rates, and 1\u2010year OS rates in the LT and NGT\u2010G groups were 18.8% and 18.1%, 30.0% and 31.7%, and 99.1% and 96.6%, respectively; no significant differences were observed between both groups. In the NGT\u2010G group, a negative colonic contrast at 24\u00a0h demonstrated a higher tendency for future recurrence compared with a positive colonic contrast at 24\u00a0h (1\u2010year recurrence rate: negative contrast, 46.9% <jats:italic>vs<\/jats:italic> positive contrast, 27.6%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Gastrografin through a nasogastric tube followed by LT can be a promising treatment strategy for ASBO, with long\u2010term efficacies equivalent to initial LT placement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.15681","type":"journal-article","created":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T15:33:43Z","timestamp":1630683223000},"page":"111-116","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Long\u2010term outcomes of nasogastric tube with Gastrografin for adhesive small bowel obstruction"],"prefix":"10.1111","volume":"37","author":[{"given":"Hirotada","family":"Nishie","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6048-0021","authenticated-orcid":false,"given":"Takaya","family":"Shimura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Sciences  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahito","family":"Katano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Sciences  Nagoya 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