{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:46:22Z","timestamp":1774957582005,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T00:00:00Z","timestamp":1659225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Early readmissions of spontaneous bacterial peritonitis (SBP) are often associated with poor outcomes. We compared characteristics and outcomes for index and 30\u2010day readmissions of SBP in the USA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed the Nationwide Readmissions Database for 2018 to identify all adult (\u2265\u00a018\u00a0years) 30\u2010day readmissions of SBP in the USA. Hospitalization characteristics and outcomes for index and 30\u2010day readmissions of SBP were compared. Independent predictors of 30\u2010day readmissions were also identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2018, of the 5,797 index admissions for SBP, 30% (1726) were readmitted within 30\u00a0day. At the time of readmission, the most common admitting diagnosis was alcoholic cirrhosis of the liver with ascites (11.8%) followed by sepsis due to an unspecified organism (9.2%). SBP as an admitting diagnosis was identified for only 8.3% of these 30\u2010day readmissions. Compared with index admissions, 30\u2010day readmissions of SBP had a lower mean age (56.1 <jats:italic>vs<\/jats:italic> 58.6\u00a0years, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) without a statistically significant difference for gender. Furthermore, 30\u2010day readmissions of SBP were associated with significantly higher odds of inpatient mortality (10% <jats:italic>vs<\/jats:italic> 4.9%, OR: 2.15, 95% CI: 1.66\u20132.79, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and mean total hospital charge ($85,031 <jats:italic>vs<\/jats:italic> $56,000, mean difference: 29,032, 95% CI: 12,867\u201345,197, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) compared with index admissions. The presence of chronic pulmonary disease, liver failure, inpatient dialysis, and discharge against medical advice were identified as independent predictors for increased 30\u2010day readmissions of SBP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The 30\u2010day readmission rate of SBP was 30% and these readmissions were associated with higher odds of inpatient mortality compared with index admissions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.15965","type":"journal-article","created":{"date-parts":[[2022,7,23]],"date-time":"2022-07-23T05:18:55Z","timestamp":1658553535000},"page":"2067-2073","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early readmissions of spontaneous bacterial peritonitis in the USA: Insights into an emerging challenge"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8544-9039","authenticated-orcid":false,"given":"Dushyant Singh","family":"Dahiya","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Central Michigan University College of Medicine  Saginaw Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2506-8602","authenticated-orcid":false,"given":"Madhusudhan R","family":"Sanaka","sequence":"additional","affiliation":[{"name":"Director of Third\u2010Space Endoscopy, Department of Gastroenterology, Hepatology and Nutrition Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4788-8572","authenticated-orcid":false,"given":"Asim","family":"Kichloo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Central Michigan University College of Medicine  Saginaw Michigan USA"},{"name":"Department of Internal Medicine Samaritan Medical Center  Watertown New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8581-1408","authenticated-orcid":false,"given":"Amandeep","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Wachala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Samaritan Medical Center  Watertown New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4074-6395","authenticated-orcid":false,"given":"Abhilash","family":"Perisetti","sequence":"additional","affiliation":[{"name":"Parkview Cancer Institute  Fort Wayne Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9433-9042","authenticated-orcid":false,"given":"Hemant","family":"Goyal","sequence":"additional","affiliation":[{"name":"The Wright Center for Graduate Medical Education  Scranton Pennsylvania USA"},{"name":"Department of Internal Medicine Mercer University School of Medicine  Macon Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1343-9939","authenticated-orcid":false,"given":"Rajat","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hepatology and Nutrition Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9456-4581","authenticated-orcid":false,"given":"Hafeez","family":"Shaka","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine John H. 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