{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:02:16Z","timestamp":1789048936715,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,10,4]],"date-time":"2022-10-04T00:00:00Z","timestamp":1664841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopic post\u2010papillectomy bleeding is a serious adverse event with a prevalence ranging from 2% to 45.3%. Conventional hemostatic methods, including diluted epinephrine injection before papillectomy or argon plasma coagulation after papillectomy, did not show a preventive role in reducing immediate or delayed post\u2010papillectomy bleeding. Therefore, we aimed to assess the efficacy and safety of a hemostatic powder spray for post\u2010papillectomy bleeding and compare with those of conventional modalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent endoscopic papillectomy were enrolled in five tertiary hospitals. The group was divided into hemostatic spray and conventional control groups according to the bleeding control methods. The main outcome measurements were delayed bleeding rate and any adverse events related to the procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 40 patients who received a hemostatic spray (<jats:italic>n<\/jats:italic>\u00a0=\u00a018) or conventional hemostatic methods (<jats:italic>n<\/jats:italic>\u00a0=\u00a022) after endoscopic papillectomy were included. The prevalence of delayed bleeding was not different in the two groups: 27.8% and 36.4% in hemostatic spray and conventional control groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.564), respectively. The adverse events such as post\u2010papillectomy pancreatitis and cholangitis were not different in the two groups. There were no procedure\u2010related mortalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hemostatic spray is technically feasible and safe for the prevention or management of post\u2010papillectomy bleeding. Hemostatic spray can be one of the options for post\u2010papillectomy bleeding control methods owing to its convenient use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16004","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T22:25:50Z","timestamp":1663712750000},"page":"2138-2144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Efficacy analysis of hemostatic spray following endoscopic papillectomy: A multicenter comparative study"],"prefix":"10.1111","volume":"37","author":[{"given":"Kyong Joo","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hallym University Dongtan Sacred Heart Hospital Hallym University College of Medicine  Hwaseong Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3545-9183","authenticated-orcid":false,"given":"Tae Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Soonchunhyang University College of Medicine  Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Hee","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5632-7091","authenticated-orcid":false,"given":"Jong Jin","family":"Hyun","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Korea University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4937-6167","authenticated-orcid":false,"given":"Sung Ill","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6178-8338","authenticated-orcid":false,"given":"Seok","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Inha University College of Medicine  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Seok","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Inha University College of Medicine  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Kook","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Soonchunhyang University College of Medicine  Cheonan Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don Haeng","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Inha University College of Medicine  Incheon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Ki","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Gangnam Severance Hospital Yonsei University College of Medicine  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Heum","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine Soonchunhyang University College of Medicine  Cheonan 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