{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T21:20:32Z","timestamp":1785792032677,"version":"3.56.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T00:00:00Z","timestamp":1667779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006484","name":"Vifor Pharma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006484","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Many patients experiencing acute gastrointestinal bleeding (GIB) require iron supplementation to treat subsequent iron deficiency (ID) or iron\u2010deficiency anemia (IDA). Guidelines regarding management of these patients are lacking. We aimed to identify areas of unmet need in patients with ID\/IDA following acute GIB in terms of patient management and physician guidance. We formed an international working group of gastroenterologists to conduct a narrative review based on PubMed and EMBASE database searches (from January 2000 to February 2021), integrated with observations from our own clinical experience. Published data on this subject are limited and disparate, and those relating to post\u2010discharge outcomes, such as persistent anemia and re\u2010hospitalization, are particularly lacking. Often, there is no post\u2010discharge follow\u2010up of these patients by a gastroenterologist. Acute GIB\u2010related ID\/IDA, however, is a prevalent condition both at the time of hospital admission and at hospital discharge and is likely underdiagnosed and undertreated. Despite limited data, there appears to be notable variation in the prescribing of intravenous (IV)\/oral iron regimens. There is also some evidence suggesting that, compared with oral iron, IV iron may restore iron levels faster following acute GIB, have a better tolerability profile, and be more beneficial in terms of quality of life. Gaps in patient care exist in the management of acute GIB\u2010related ID\/IDA, yet further data from large population\u2010based studies are needed to confirm this. We advocate the formulation of evidence\u2010based guidance on the use of iron therapies in these patients, aiding a more standardized best\u2010practice approach to patient care.<\/jats:p>","DOI":"10.1111\/jgh.16033","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T03:29:29Z","timestamp":1666322969000},"page":"23-33","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Management of iron\u2010deficiency anemia following acute gastrointestinal hemorrhage: A narrative analysis and review"],"prefix":"10.1111","volume":"38","author":[{"given":"Angel","family":"Lanas","sequence":"first","affiliation":[{"name":"Servicio de Aparato Digestivo, Hospital Cl\u00ednico University of Zaragoza, IIS Arag\u00f3n  Zaragoza Spain"},{"name":"CIBERehd  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane M","family":"Andrews","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Faculty of Health Science University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-4068","authenticated-orcid":false,"given":"James","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Surgery, Prince of Wales Hospital The Chinese University of Hong Kong  Hong Kong SAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8873-7426","authenticated-orcid":false,"given":"Murat","family":"Toruner","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ankara University School of Medicine  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E","family":"Bromley","sequence":"additional","affiliation":[{"name":"EpiMed Communications  Abingdon Oxfordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1521-3354","authenticated-orcid":false,"given":"Ian M","family":"Gralnek","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology and Hepatology Emek Medical Center  Afula Israel"},{"name":"Rappaport Faculty of Medicine Technion\u2010Israel Institute of Technology  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.4997\/jrcpe.2017.303"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.228437"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1310006"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.164"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/2040622310373675"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2017.17593"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.12809\/hkmj187348"},{"key":"e_1_2_6_9_1","first-page":"45","article-title":"Practical management of anaemia after a gastrointestinal bleed","volume":"8","author":"Gralnek IM","year":"2019","journal-title":"EMJ Gastroenterol"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15327"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12556"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v7.i1.139"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13486"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.14440"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000001282"},{"key":"e_1_2_6_16_1","first-page":"A4583","article-title":"Lack of follow\u2010up of anaemia after discharge from an upper gastrointestinal bleeding centre","volume":"60","author":"Bager P","year":"2013","journal-title":"Dan. 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