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However, an overlap of symptom categories frequently occurs and has a negative impact on treatment outcomes. There is a lack of guidance on their management. An Asian Pacific Association of Gastroenterology (APAGE) working group was set up to develop clinical practice guidelines for management of patients with functional dyspepsia (FD) who have an overlap with another functional gastrointestinal disorder: FD with gastroesophageal reflux (FD\u2010GERD), epigastric pain syndrome with irritable bowel syndrome (EPS\u2010IBS), postprandial distress syndrome with IBS (PDS\u2010IBS), and FD\u2010Constipation. We identified putative pathophysiology to provide a basis for treatment recommendations. A management algorithm is presented to guide primary and secondary care clinicians.<\/jats:p>","DOI":"10.1111\/jgh.16046","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T02:10:11Z","timestamp":1667355011000},"page":"197-209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Asia\u2010Pacific guidelines for managing functional dyspepsia overlapping with other gastrointestinal symptoms"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4813-0053","authenticated-orcid":false,"given":"Kok\u2010Ann","family":"Gwee","sequence":"first","affiliation":[{"name":"Department of Medicine, Yong Loo Lin School of Medicine National University of Singapore, and The Gastroenterology Group, Gleneagles Hospital  Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeong 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