{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T21:11:57Z","timestamp":1769548317882,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Stent\u2010induced ductal change (SIDC) is a complication of endoscopic pancreatic stenting (EPS) in patients with chronic pancreatitis (CP). However, the evaluation of SIDC associated with S\u2010type pancreatic plastic stent (PS) and large\u2010caliber PS, such as 10\u00a0Fr, is limited. This study aimed to analyze the SIDC of the main pancreatic duct (MPD) associated with 10\u2010Fr S\u2010type PS in patients with CP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2008 and December 2021, 132 patients with CP in whom a 10\u2010Fr S\u2010type PS had been installed by EPS were retrospectively reviewed. The SIDC incidence rate was examined, and the clinical features of patients with and without SIDC were investigated, including the outcomes for detected SIDC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Stent\u2010induced ductal change during EPS was confirmed in 41 patients (31.1%) of 132 patients at a site coincident with the PS tip or distal flap in the MPD. All patients were asymptomatic during the development of SIDC. Morphological changes in the MPD were detected as elevated (75.6%) or bearing stricture changes (24.4%). A total of 90.2% of SIDC developed after the first 10\u2010Fr PS installation. No significant differences were noted between the patients with and without SIDC. The outcomes of continued PS installment for SIDC showed persistence and secondary change.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Stent\u2010induced ductal change\u2010associated 10\u2010Fr PS installation was performed in just under one\u2010third of the patients, indicating a substantial incidence rate and a possible development of SIDC from early stages onwards. More emphasis should be placed on SIDC as the complication.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16052","type":"journal-article","created":{"date-parts":[[2022,11,5]],"date-time":"2022-11-05T18:39:42Z","timestamp":1667673582000},"page":"112-118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Focal pancreatic ductal change induced by 10\u2010Fr S\u2010type plastic stent in chronic pancreatitis"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3294-8990","authenticated-orcid":false,"given":"Kensuke","family":"Takuma","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Toho University Omori Medical Center  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Okano","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Toho University Omori Medical Center  Tokyo 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