{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T19:15:44Z","timestamp":1780427744357,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T00:00:00Z","timestamp":1670803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The adenoma detection rate (ADR), which is closely related to bowel preparation, is the most important factor for colonoscopy quality assessment. New oral sulfate tablets (OSTs) have been developed to improve bowel preparation compliance. This study evaluated the efficacy of OSTs in terms of the ADR and bowel preparation status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical records of subjects under the age of 65 who underwent colonoscopy from March 2019 to February 2021 were retrospectively reviewed. Polyethylene glycol with ascorbic acid (PEG\u2010A) was used as a bowel preparation for the first half of the study period, and OSTs were used for the second half. In total, 16\u2009971 subjects were included in the study: 9199 (54.2%) used PEG\u2010A, and 7772 (45.8%) used OSTs. Bowel cleansing quality was assessed by the Boston Bowel Preparation Scale (BBPS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age was 50\u00a0years. The rate of adequate bowel preparation was higher in the OST group than in the PEG\u2010A group (97.2% <jats:italic>vs<\/jats:italic> 95.0%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). The mean BBPS was also higher in the OST group (8.02 <jats:italic>vs<\/jats:italic> 7.75, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). The adenomas per colonoscopy (APC), the ADR and the sessile serrated polyp detection rate (SSPDR) were higher in the OST group than in the PEG\u2010A group (APC 0.56\u00a0\u00b1\u00a01.01 <jats:italic>vs<\/jats:italic> 0.48\u00a0\u00b1\u00a00.91, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001; ADR 34.5% <jats:italic>vs<\/jats:italic> 30.7%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001; SSPDR 5.2% <jats:italic>vs<\/jats:italic> 3.3%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with PEG\u2010A, OSTs yielded superior APC, ADRs, SSPDRs, and better bowel cleanliness. Therefore, OSTs are a good alternative for patients who have difficulty taking large\u2010volume bowel preparation formulations.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16079","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T13:34:15Z","timestamp":1669901655000},"page":"410-415","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Efficacy of oral sulfate tablets for bowel preparation and adenoma detection rate"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9459-9250","authenticated-orcid":false,"given":"Ji Hyun","family":"Song","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Ho","family":"Bae","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8175-5813","authenticated-orcid":false,"given":"Jeong Yoon","family":"Yim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Healthcare Research Institute Seoul National University Hospital Healthcare System Gangnam Center  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,12]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"National Cancer Information Center.National cancer screening services [Internet]. 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