{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T07:26:46Z","timestamp":1785742006513,"version":"3.56.0"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T00:00:00Z","timestamp":1678492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Upper gastrointestinal bleeding (UGIB) is a common emergency, with high rates of hospitalization and in\u2010patient mortality compared to other gastrointestinal diseases. Despite readmission rates being a common quality metric, little data are available for UGIBs. This study aimed to determine readmission rates for patients discharged following an UGIB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Adhering to PRISMA guidelines, MEDLINE, Embase, CENTRAL, and Web of Science were searched to October 16, 2021. Randomized and non\u2010randomized studies that reported hospital readmission for patients following an UGIB were included. Abstract screening, data extraction, and quality assessment were conducted in duplicate. A random\u2010effects meta\u2010analysis was performed, with statistical heterogeneity measured using <jats:italic>I<\/jats:italic><jats:sup>2<\/jats:sup>. The GRADE framework, with a modified Downs and Black tool, was used to determine certainty of evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy studies were included of 1847 screened abstracted, with moderate interrater reliability. Within these studies, 4\u00a0292\u00a0714 patients were analyzed with a mean age of 66.6\u00a0years, and 54.7% male. UGIB had a 30\u2010day all\u2010cause readmission rate of 17.4% (95% confidence interval [CI] 16.7\u201318.2%), stratification revealed a higher rate for variceal UGIB [19.6% (95% CI 17.6\u201321.5%)] than non\u2010variceal [16.8% (95% CI 16.0\u201317.5%)]. Only one third were readmitted due to recurrent UGIB (4.8% [95% CI 3.1\u20136.4%]). UGIB due to peptic ulcer bleeding had the lowest 30\u2010day readmission rate [6.9% (95% CI 3.8\u201310.0%)]. Certainty of evidence was low or very low for all outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Almost one in five patients discharged after an UGIB are readmitted within 30\u00a0days. These data should prompt clinicians to reflect on their own practice to identify areas of strength or improvement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16153","type":"journal-article","created":{"date-parts":[[2023,2,20]],"date-time":"2023-02-20T13:09:33Z","timestamp":1676898573000},"page":"692-702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["30\u2010day readmission rates among upper gastrointestinal bleeds: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7465-3264","authenticated-orcid":false,"given":"Cody L","family":"Dunne","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bronwyn","family":"Delacruz","sequence":"additional","affiliation":[{"name":"Cumming School of Medicine University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4387-9612","authenticated-orcid":false,"given":"Lauren C","family":"Bresee","sequence":"additional","affiliation":[{"name":"Department of Community Health Sciences University of Calgary  Calgary Canada"},{"name":"O'Brien Institute for Public Health University of Calgary  Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gle.2014.09.027"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620\u2010017\u20104882\u20106"},{"key":"e_1_2_7_4_1","unstructured":"MilenkovicM RussoCA ElixhauserA.Statistical brief #12 hospital stays for gastrointestinal diseases 2004 [Internet]. [Rockland (MD)]: Mirjana Milenkovic; c2006 [2006 Feb; cited 2022 Aug 28]. Available from:https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK63496\/"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.08.063"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.20"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.111.000101"},{"key":"e_1_2_7_8_1","unstructured":"US Centers for Medicare & Medicaid Services.Outcome Measures. C2021 [cited 2022 Sept 12]. 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