{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T21:16:54Z","timestamp":1762377414705,"version":"3.41.0"},"reference-count":27,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T00:00:00Z","timestamp":1688688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003670","name":"National Evidence-based Healthcare Collaborating Agency","doi-asserted-by":"publisher","award":["HC20C0062"],"award-info":[{"award-number":["HC20C0062"]}],"id":[{"id":"10.13039\/501100003670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008746","name":"National Cancer Center","doi-asserted-by":"publisher","award":["HA21C0110"],"award-info":[{"award-number":["HA21C0110"]}],"id":[{"id":"10.13039\/100008746","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Portosystemic shunt embolization (PSSE) is a promising treatment for hepatic encephalopathy (HEP) and gastric varix (GV) in cirrhotic patients with a spontaneous portosystemic shunt. However, PSSE may worsen portal hypertension causing hepatorenal syndrome, liver failure, and mortality. This study aimed to develop and validate a prognostic model that helps identify patients with a risk of poor short\u2010term survival after PSSE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 188 patients who underwent PSSE for recurrent HEP or GV at a tertiary center in Korea. To develop a prediction model for 6\u2010month survival after PSSE, Cox proportional\u2010hazard model was used. The developed model was validated in a separate cohort of 184 patients from two other tertiary centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In multivariable analysis, the 1\u2010year overall survival after PSSE was significantly associated with baseline levels of serum albumin, total bilirubin, and international normalized ratio (INR). We therefore developed the albumin\u2010bilirubin\u2010INR (ABI) score by assigning 1 point each for albumin &lt;\u00a03.0\u00a0g\/dL, total bilirubin \u2265\u00a01.5\u00a0mg\/dL, and INR\u00a0\u2265\u00a01.5. Time\u2010dependent areas under the curve of the ABI score for predicting 3\u2010month and 6\u2010month survival were 0.85 and 0.85 in the development cohort and 0.83 and 0.78 in the validation cohort, indicating good discrimination performance. The ABI score showed a better discrimination and calibration performance than the model for end\u2010stage liver disease and the Child\u2013Pugh scores, especially in high\u2010risk patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ABI score is a simple prognostic model that helps decide whether to proceed with PSSE for the prevention of HEP or GV bleeding in patients with spontaneous portosystemic shunt.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16280","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T11:56:07Z","timestamp":1688730967000},"page":"1629-1636","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A model for predicting poor survival in patients with cirrhosis undergoing portosystemic shunt embolization"],"prefix":"10.1111","volume":"38","author":[{"given":"Won\u2010Mook","family":"Choi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Liver Center, Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seo Yeon","family":"Yoo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Liver Center, Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong\u2010In","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Republic of Korea"},{"name":"Department of Gastroenterology Chung\u2010Ang University Gwangmyeong Hospital  Gwangmyeong Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seungbong","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Korea University College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7113-3623","authenticated-orcid":false,"given":"Young Seok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, Soonchunhyang University Bucheon Hospital Soonchunhyang University College of Medicine  Bucheon Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7126-5554","authenticated-orcid":false,"given":"Dong Hyun","family":"Sinn","sequence":"additional","affiliation":[{"name":"Department of Medicine, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6898-6617","authenticated-orcid":false,"given":"Sang Hyun","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Il","family":"Gwon","sequence":"additional","affiliation":[{"name":"Department of Radiology, Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1544-577X","authenticated-orcid":false,"given":"Young\u2010Suk","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Liver Center, Asan Medical Center University of Ulsan College of Medicine  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.01.028"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.01.027"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2017.0064"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(88)90501-X"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20905"},{"key":"e_1_2_6_7_1","first-page":"450","article-title":"Clinical and portal hemodynamic features in cirrhotic patients having a large spontaneous splenorenal and\/or gastrorenal shunt","volume":"81","author":"Ohnishi K","year":"1986","journal-title":"Am. 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