{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:30:02Z","timestamp":1747186202638,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T00:00:00Z","timestamp":1692057600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>We aim to systematically investigate gastrointestinal (GI) hospitalizations in the United States during the early phase of the COVID\u201019 pandemic on a national level and the consequence that may inform practice and policies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cross\u2010sectional analysis of adult hospitalizations with GI\u2010related diagnoses or procedures in the United States in 2020 was used, with hospitalizations from 2016 to 2019 used for contextual information.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hospitalizations with principal and secondary GI diagnoses decreased by 13.3% and 8.2% from 2019 to 2020, respectively. Most GI diagnoses decreased in 2020, with a few exceptions including alcoholic liver disease (increased by 7.8% as a principal diagnosis) and acute liver failure (increased by 11.6% as a secondary diagnosis). The mortality rate of hospitalizations with GI disease increased in 2020 compared with 2019 (for principal diagnosis: adjusted odds ratio 1.08, 95% confidence interval 1.03\u20131.13, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.001; for secondary diagnosis: adjusted odds ratio 1.10, 95% confidence interval 1.07\u20131.13, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Most GI procedures decreased except for a notable 8.3% increase in gastrostomy. The per\u2010GI\u2010hospitalization rate of procedures increased for hospitalizations with a principal GI diagnosis (56.4% <jats:italic>vs<\/jats:italic> 55.6%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.003) or unchanged for hospitalizations with secondary GI diagnoses (18.3% <jats:italic>vs<\/jats:italic> 18.2%, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.512).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The COVID\u201019 pandemic resulted in a decrease in the volume of GI hospitalizations and procedures in 2020, but there was an increase in the mortality rate and some specific diagnoses including alcoholic liver disease and acute liver failure. These findings will likely enlighten future research and healthcare resource allocation for GI diseases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16318","type":"journal-article","created":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T08:39:28Z","timestamp":1692088768000},"page":"1971-1979","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Gastrointestinal hospitalization during COVID\u201019 pandemic in the United States: Analysis of a nationwide inpatient sample"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0723-5913","authenticated-orcid":false,"given":"Yichen","family":"Wang","sequence":"first","affiliation":[{"name":"Mercy Internal Medicine Service Trinity Health of New England  Springfield Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9986-5124","authenticated-orcid":false,"given":"Yuting","family":"Huang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Zheng","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyu","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Thyroid and Breast Surgery The Second Hospital of Anhui Medical University  He Fei China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keming","family":"Yang","sequence":"additional","affiliation":[{"name":"Clinical and Translational Epidemiology Unit and Division of Gastroenterology Massachusetts General Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1717-6988","authenticated-orcid":false,"given":"Maoyin","family":"Pang","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Mayo Clinic  Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,15]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"Mortality in the United States, 2020","volume":"427","author":"Murphy SL","year":"2021","journal-title":"NCHS Data Brief"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000001541"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.09.037"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(20)30392\u20102"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20101253(21)00005\u20104"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.03.072"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.07.028"},{"volume-title":"Healthcare cost and utilization project data use agreement course","author":"DUA Training \u2010 Accessible Version","key":"e_1_2_6_9_1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199801000-00004"},{"key":"e_1_2_6_11_1","unstructured":"Population and Housing Unit Estimates Tables.https:\/\/www.census.gov\/programs\u2010surveys\/popest\/data\/tables.html. 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