{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T13:30:57Z","timestamp":1781530257235,"version":"3.54.1"},"reference-count":41,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T00:00:00Z","timestamp":1692835200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The study aims to assess the value of different risk stratifications in diagnosing early gastric cancer (GC) and explore risk factors based on Kyoto gastritis classification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was a single\u2010centered cross\u2010sectional study; all epidemiological data and endoscopic findings were obtained prospectively. To evaluate the proportion of GC in each risk stratification and to compare the diagnostic performance of different methods using the receiver operating characteristic curve, univariable and multivariable analyses were used to explore the correlation between endoscopic findings and GC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 240 subjects were enrolled, and the diagnostic efficacy of the Kyoto Classification Score was similar to Operative Link on Gastric Intestinal Metaplasia Assessment (OLGIM) stage, and the accuracy was higher than that of the Japanese scoring system and OLGA stage. Moderate atrophy (odds ratio [OR]\u00a0=\u00a03.52, 95% confidence interval [CI]: 1.52\u20138.16), severe atrophy (OR\u00a0=\u00a04.96, 95% CI: 1.75\u201314.04), map\u2010like redness (OR\u00a0=\u00a09.89, 95% CI: 1.16\u201384.15), and xanthelasma (OR\u00a0=\u00a03.57, 95% CI: 1.15\u201311.15) were independent risk factors for GC. The simplified Kyoto classification (area under the receiver operating characteristic [AUROC]\u00a0=\u00a00.76, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.58) based on multivariable analysis demonstrated favorable diagnostic value compared with traditional Kyoto classification score (AUROC\u00a0=\u00a00.74).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study confirms the value of the Kyoto classification score and the OLGIM stage in the risk stratification of GC. Simplified Kyoto classification is also promising in risk assessment of GC but still requires validation in the population.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16324","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T05:19:58Z","timestamp":1692940798000},"page":"1988-1997","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of different risk stratifications for gastric cancer and establishing a simplified risk\u2010scoring model based on the Kyoto classification"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4954-6816","authenticated-orcid":false,"given":"Pengyue","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Gastroenterology The First Affiliated Hospital of Anhui Medical University  Hefei China"},{"name":"Department of Infectious Diseases The Second Hospital of Anhui Medical University  Hefei 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