{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T15:53:49Z","timestamp":1772207629254,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,6]],"date-time":"2023-11-06T00:00:00Z","timestamp":1699228800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Accurate assessment of invasion depth of early rectal neoplasms is essential for optimal therapy. We aimed to compare three\u2010dimensional endorectal ultrasound (3D\u2010ERUS) with magnification chromoendoscopy (MCE) regarding their accuracy in assessing parietal invasion depth (T).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with middle and distal rectum neoplasms were prospectively included. Two providers blinded to each other's assessment performed 3D\u2010ERUS and MCE, respectively. The T stage assessed through ERUS was compared to the MCE evaluation. The results were compared to the surgical specimen anatomopathological report. Sensitivity, specificity, accuracy, positive (PPV), and negative (NPV) predictive values were calculated for the T stage and for the final therapy (local excision or radical surgery).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 8\u00a0years, 70 patients were enrolled, and all underwent both exams. MCE and ERUS showed an accuracy of 94.3% and 85.7%, sensitivity of 83.7 and 93.3%, specificity of 96.4 and 83.6%, PPV of 86.7 and 60.9%, and NPV of 96.4 and 97.9%, respectively. Kappa for T stage assessed through ERUS was 0.64 and 0.83 for MCE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MCE and 3D\u2010ERUS had good diagnostic performance, but the endoscopic method had higher accuracy. Both methods reliably assessed lesion extension, circumferential involvement, and distance from the anal verge.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16382","type":"journal-article","created":{"date-parts":[[2023,11,7]],"date-time":"2023-11-07T00:10:17Z","timestamp":1699315817000},"page":"346-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparing three\u2010dimensional endorectal ultrasound and magnification chromoendoscopy for early rectal neoplasia invasion depth assessment"],"prefix":"10.1111","volume":"39","author":[{"given":"Rodrigo Ambar","family":"Pinto","sequence":"first","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6709-9979","authenticated-orcid":false,"given":"F\u00e1bio Shiguehissa","family":"Kawaguti","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5772-1747","authenticated-orcid":false,"given":"Cintia Mayumi Sakurai","family":"Kimura","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"},{"name":"Department of Surgery Stanford School of Medicine  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaac Jos\u00e9 Felippe","family":"Corr\u00eaa Neto","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caio S\u00e9rgio Rizkallah","family":"Nahas","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Frederico Sparapan","family":"Marques","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo Alfonso","family":"Bustamante\u2010Lopez","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulysses","family":"Ribeiro\u2010Jr","sequence":"additional","affiliation":[{"name":"Division of Gastrointestinal Surgery Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fauze","family":"Maluf\u2010Filho","sequence":"additional","affiliation":[{"name":"Division of Endoscopy Instituto do C\u00e2ncer do Estado de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9rgio Carlos","family":"Nahas","sequence":"additional","affiliation":[{"name":"Division of Colon and Rectal Surgery Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-826104"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-004-1339-4"},{"key":"e_1_2_6_4_1","article-title":"Long\u2010term outcomes of endoscopic submucosal dissection and transanal endoscopic microsurgery for the treatment of rectal tumors","author":"Kimura CMS","year":"2020","journal-title":"J. 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