{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T11:52:50Z","timestamp":1779105170971,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:00:00Z","timestamp":1707955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Lack of awareness disturbs proper care for hepatitis C virus (HCV) infections in patients undergoing surgery. We investigated the status of HCV screening, confirmation, and treatment in patients who underwent surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent surgery at a tertiary academic center between 2019 and 2021 were eligible for this retrospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Between 2019 and 2021, 96\u00a0894 patients (40\u00a0121 males; 41.4%) who underwent surgery under general anesthesia were recruited. The median age of the participants was 55.0\u00a0years. Of the 83\u00a0920 (86.6%) patients who tested positive for anti\u2010HCV antibodies, 576 (0.7%) showed positive results, with a higher proportion of patients with diabetes mellitus (32.6% <jats:italic>vs<\/jats:italic> 18.5%), hypertension (50.5% <jats:italic>vs<\/jats:italic> 28.6%), liver cirrhosis (13.2% <jats:italic>vs<\/jats:italic> 1.7%), and unfavorable laboratory test results when compared with those with negative results (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). HCV RNA was tested in 215 patients (37.3%), with a positivity rate of 20.5% (<jats:italic>n<\/jats:italic>\u00a0=\u00a044). Of the 44 patients, 42 (95.5%) were referred for antiviral treatment, and 29 (69.0%) were successfully treated with direct\u2010acting antiviral therapy. HCV RNA confirmation rates were higher in the Department of Hepatobiliary and Transplant Surgery (76.6%) than in the other surgical departments (25.0\u201333.5%) (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The proportion of patients who were positive for anti\u2010HCV antibodies and failed to receive proper management after surgery was not negligible. Increased awareness of HCV infection among surgeons through appropriate education may be required.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16506","type":"journal-article","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T10:14:35Z","timestamp":1707992075000},"page":"1155-1163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hepatitis C virus infection in patients undergoing surgery in a single tertiary academic center"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2371-0967","authenticated-orcid":false,"given":"Jae Seung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3552-3560","authenticated-orcid":false,"given":"Hye Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5381-230X","authenticated-orcid":false,"given":"Mi Na","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5363-2496","authenticated-orcid":false,"given":"Beom Kyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6324-2224","authenticated-orcid":false,"given":"Jun Yong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8327-3439","authenticated-orcid":false,"given":"Do Young","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3629-4624","authenticated-orcid":false,"given":"Sang Hoon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9658-8050","authenticated-orcid":false,"given":"Seung Up","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine  Seoul South Korea"},{"name":"Yonsei Liver Center, Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0193"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(22)00386-7"},{"key":"e_1_2_7_4_1","volume-title":"Global Health Sector Strategy on Viral Hepatitis 2016\u20132021. 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