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The world\u2010wide prevalence reduces from 4.2% in 1980 to 3.2% in 2020 study. CHB patients receiving long\u2010term antiviral therapies significantly improve the clinical outcomes, saving from end\u2010stage liver diseases. Despite of these impressive progresses, to meet the WHO sustained development goals (SDG) for CHB control, a 90% reduction of incidence and a 65% reduction of mortality in year 2030, there is still a long way to go. In this review, four ongoing approaches have been proposed: (i) A continuous monitoring of long\u2010term vaccine efficacy in vaccinated populations; (ii) consolidating the hepatitis B virus vaccination program against vaccine hesitancy and limited resources; (iii) rolling\u2010out current oral antivirals to more CHB patients not only for diseases treatment but also for infection preventions; and (iv) development of curative therapies, both friendly\u2010to\u2010dispense and affordable. A coherent and persevere efforts by the society may succeed and achieve the SDG for CHB in the future.<\/jats:p>","DOI":"10.1111\/jgh.16528","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T02:13:51Z","timestamp":1709086431000},"page":"1033-1039","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Challenges for hepatitis B control in Asia\u2010Pacific areas: Consolidating vaccination and rolling\u2010out antiviral therapies"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8316-3785","authenticated-orcid":false,"given":"Pei\u2010Jer","family":"Chen","sequence":"first","affiliation":[{"name":"Hepatitis Research Center National Taiwan University Hospital  Taipei Taiwan"},{"name":"Department of Internal Medicine National Taiwan University Hospital  Taipei Taiwan"},{"name":"National Taiwan University College of Medicine  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,27]]},"reference":[{"key":"e_1_2_12_2_1","unstructured":"Global Burden of Disease Study 2016 (GBD 2016) Population Estimates 1950\u20102016. 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