{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T19:34:35Z","timestamp":1778700875921,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background\/Aims<\/jats:title><jats:p>Endoscopic sphincterotomy (EST) is a standard treatment for common bile duct (CBD) stones. Endoscopic sphincterotomy combined with endoscopic papillary large balloon dilation (EST\u2010EPLBD) is an effective treatment for difficult CBD stones. This study aims to evaluate and compare the effectiveness and adverse effects of EST\u2010EPLBD and EST in treating large CBD stones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed the data of 85 patients with large CBD stones who underwent either EST or EST\u2010EPLBD, resulting in successful CBD stone extraction from January 2018 to June 2022. Propensity score inverse weighting was performed to reduce the possible bias in baseline characteristics between the two treatment groups. The success rate of complete stone removal in the first session, mechanical lithotripsy use, and adverse events were analyzed by multivariable risk regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rate of complete stone removal in one session of the EST\u2010EPLBD group was higher than that of the EST group at 28.78% (95% confidence interval [CI] 4.43, 50.1; <jats:italic>p<\/jats:italic>\u2009=\u20090.003). Mechanical lithotripsy use was decreased in the EST\u2010EPLBD group by 25.81% (95% CI 42.33,9.28; <jats:italic>p<\/jats:italic>\u2009=\u20090.002). However, the incidence of adverse events is comparable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EST\u2010EPLBD may be utilized in the treatment of CBD stones that exceed a diameter of 10\u2009mm. The EST\u2010EPLBD increased the rate of complete stone removal in a single session and reduced the need for mechanical lithotripsy. Conversely, the incidence rate of adverse events is similar.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16825","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T04:13:41Z","timestamp":1732162421000},"page":"510-519","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparative Success Rate and Adverse Effects of Endoscopic Sphincterotomy Versus Endoscopic Papillary Large Balloon Dilation in Large Common Bile Duct Stones Removal. A Propensity Scores Inverse Weighting Analysis"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7746-2631","authenticated-orcid":false,"given":"Chote","family":"Wongkanong","sequence":"first","affiliation":[{"name":"Department of Surgery Pattani Hospital  Pattani Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8579-1547","authenticated-orcid":false,"given":"Thawee","family":"Ratanachu\u2010ek","sequence":"additional","affiliation":[{"name":"Surgical Endoscopy Unit, Department of Surgery Rajavithi Hospital, Department of Medical Services Ministry of Public Health  Nonthaburi Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8977-2995","authenticated-orcid":false,"given":"Jayanton","family":"Patumanond","sequence":"additional","affiliation":[{"name":"Center for Clinical Epidemiology &amp; Clinical Statistics, Faculty of Medicine Chiang Mai 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