{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:08:35Z","timestamp":1773922115232,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T00:00:00Z","timestamp":1733270400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The impact of different anti\u2010thrombotic agents on patients with suspected small bowel bleeding (SSBB) who underwent balloon\u2010assisted enteroscopy (DAE) is unclear. We aimed to examine the clinical effects and predictive factors of DAE based on the thromboembolic agents used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 399 patients with SSBB from a web\u2010based DAE registry across 30 medical centers in South Korea. Among them, 291 patients did not receive anti\u2010thrombotic agents, whereas 80, 22, and 6 patients received anti\u2010platelet agents, direct oral anti\u2010coagulants (DOACs), and warfarin, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Diagnostic yields were similar across groups; however, therapeutic yields differed: 25.4%, 37.5%, 63.6%, and 83.3% in patients treated with no anti\u2010thrombotic agents, anti\u2010platelets, DOACs, and warfarin, respectively (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The multivariable logistic regression revealed that patients treated with DOACs and warfarin experienced significantly higher therapeutic yields (odds ratio [OR]: 2.803 and 9.526, respectively; 95% confidence interval [CI]: 1.048\u20137.500 and 1.061\u201385.481, respectively; <jats:italic>p<\/jats:italic>\u2009=\u20090.040 and 0.044, respectively) than those treated with no anti\u2010thrombotic agents. The re\u2010bleeding rates in patients treated with no anti\u2010thrombotic agents, anti\u2010platelets, DOACs, and warfarin were 9.6%, 6.3%, 13.6%, and 50.0%, respectively (<jats:italic>p<\/jats:italic>\u2009=\u20090.069). In the multivariable logistic regression analysis, patients treated with warfarin exhibited higher re\u2010bleeding rates than those not treated with anti\u2010thrombotic agents (OR: 9.393, 95% CI: 1.809\u201348.764, <jats:italic>p<\/jats:italic>\u2009=\u20090.008).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The diagnostic yield of DAE did not differ based on the anti\u2010thrombotic agent type, whereas the therapeutic yield of DAE in DOAC and warfarin users was high. Careful monitoring for re\u2010bleeding is advised in DOAC as well as warfarin users.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16837","type":"journal-article","created":{"date-parts":[[2024,12,4]],"date-time":"2024-12-04T12:00:12Z","timestamp":1733313612000},"page":"456-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Different Types of Antithrombotic Agents on Clinical Outcomes in Patients With Small Bowel Bleeding Who Underwent Balloon\u2010Assisted Enteroscopy: A KASID Multicenter Study"],"prefix":"10.1111","volume":"40","author":[{"given":"Jihye","family":"Park","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul South Korea"},{"name":"Institute of Gastroenterology Yonsei University College of Medicine, Sinchon Severance Hospital  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin\u00a0Su","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine The Catholic University of Korea  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1166-0085","authenticated-orcid":false,"given":"Joo\u00a0Hye","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Konkuk University Medical Center Konkuk University School of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwangwoo","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Dankook University Hospital Dankook University College of Medicine  Cheonan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seong\u2010Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ewha Womans University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eui\u00a0Sun","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Ewha Womans University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4272-8003","authenticated-orcid":false,"given":"Jae\u00a0Hyun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Kosin University College of Medicine  Busan South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6970-9737","authenticated-orcid":false,"given":"Seong\u00a0Ran","family":"Jeon","sequence":"additional","affiliation":[{"name":"Institute for Digestive Research, Digestive Disease Center Soonchunhyang University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"The Small Intestine Research Group of the Korean Association for the Study of Intestinal Diseases 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