{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T05:50:14Z","timestamp":1778910614569,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Qualitative diagnosis of ulcerative colitis\u2013associated neoplasia (UCAN) is crucial for surveillance colonoscopy in patients with ulcerative colitis (UC). Although the utility of magnifying endoscopy with narrow\u2010band imaging (ME\u2010NBI) in sporadic neoplasia diagnosis has been reported, its efficacy in UCAN remains unclear. This study aimed to evaluate the usefulness of ME\u2010NBI for qualitative diagnosis of UCAN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We generated 60 ME\u2010NBI images (30 UCANs and 30 nonneoplasia lesions, including 10 polypoid and 20 nonpolypoid lesions) from patients with UC who underwent colonoscopy at our hospital between 2015 and 2023. Eleven endoscopists (seven experts and four trainees) independently assessed these images. Lesions were categorized into high\u2010 (\u2265 80%), moderate\u2010 (50%\u201379%), and low\u2010 (&lt; 50%) accuracy groups on the basis of the correct diagnostic rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall sensitivity, specificity, and correct diagnostic rates were 66.5%, 79.0%, and 71.8%, respectively. Experts tended to exhibit higher specificity than trainees (83% vs. 70%). Polypoid lesions showed higher sensitivity (92% vs. 54%) and lower specificity (61% vs. 88%) than nonpolypoid lesions. Overall, the kappa value was 0.411. In UCAN, 37%, 37%, and 24% were classified into the high\u2010, moderate\u2010, and low\u2010accuracy groups, respectively. All endoscopists assessed one case of UCAN in the low\u2010accuracy group as a nonneoplastic vessel with a surface pattern. Only two nonneoplasias were identified as having nonneoplastic vessel and surface patterns by all endoscopists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study demonstrated the usefulness of ME\u2010NBI for qualitative diagnosis, along with its limitations. A unique endoscopic diagnostic algorithm for UCAN, incorporating ME\u2010NBI and other modalities, is necessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.16877","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T04:51:37Z","timestamp":1736225497000},"page":"900-906","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Usefulness of Magnifying Endoscopy With Narrow\u2010Band Imaging for Diagnosis of Ulcerative Colitis\u2013Associated Neoplasia"],"prefix":"10.1111","volume":"40","author":[{"given":"Masafumi","family":"Nishio","sequence":"first","affiliation":[{"name":"Division of Endoscopy Yokohama City University Medical Center  Yokohama Kanagawa Japan"},{"name":"Inflammatory Bowel Disease Center Yokohama City University Medical Center  Yokohama Kanagawa 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