{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:57:25Z","timestamp":1788965845874,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>EUS\u2010guided gastroenterostomy (EUS\u2010GE) and enteral stents (ES) are minimally invasive options for managing malignant gastric outlet obstruction (mGOO). We aimed to compare EUS\u2010GE with ES with respect to clinical success assessed objectively and overall survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective review of patients &gt;\u200918\u2009years who underwent either ES or EUS\u2010GE for palliation of mGOO between January 2021 and January 2024 was done. Primary outcomes were clinical success (defined as improvement of oral intake and tolerance of higher consistency diet compared to baseline by 2 points using GOOSS) and overall survival. Secondary outcomes were adverse events, reintervention rates, and reintervention\u2010free survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One\u2010hundred and seventy\u2010two patients were included (112 ES group and 60 EUS\u2010GE). The most common background malignancy was pancreatic cancer (30.2%), followed by gall\u2010bladder cancer (26.2%). Technical success rates were similar (EUS\u2010GE 95.08% and ES 99.09%; <jats:italic>p<\/jats:italic>\u2009=\u20090.123). Clinical success was achieved more often in those who underwent EUS\u2010GE (94.7% vs. 77.5%, <jats:italic>p<\/jats:italic>\u2009=\u20090.004, OR 5.233). Overall survival (ES 112\u2009days vs. EUS\u2010GE 177\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.787) was not statistically different in the two groups. Although reintervention was needed in ES more often (18.9% vs. 3.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.005, OR 5.392), reintervention\u2010free survival (ES 93\u2009days vs. EUS\u2010GE 177\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.581) did not differ. Overall survival was lower in those who did not achieve clinical success (clinical success\u2014no, 49\u2009days; yes, 134\u2009days, <jats:italic>p<\/jats:italic>\u2009=\u20090.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EUS\u2010GE could achieve better outcomes than ES in terms of the nature of oral intake feasible with lesser need for reintervention, with patients achieving clinical success surviving longer.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jgh.70066","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T09:39:52Z","timestamp":1756546792000},"page":"2552-2559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical Success Impacts Overall Survival in Patients Undergoing Palliation for Malignant Gastric Outlet Obstruction Using Enteral Stents or Endoscopic Ultrasound Guided Gastroenterostomy"],"prefix":"10.1111","volume":"40","author":[{"given":"Akhil","family":"Mahajan","sequence":"first","affiliation":[{"name":"Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2946-8534","authenticated-orcid":false,"given":"Sridhar","family":"Sundaram","sequence":"additional","affiliation":[{"name":"Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital Homi Bhabha National Institute  Mumbai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Puri","sequence":"additional","affiliation":[{"name":"Department of Digestive Diseases and Clinical Nutrition, Tata Memorial Hospital Homi Bhabha National Institute  Mumbai 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