{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T14:42:17Z","timestamp":1779374537268,"version":"3.53.1"},"reference-count":5,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Intermittent fasting (IF) has attained considerable popularity, often advocated as an effective treatment for weight control and metabolic well\u2010being. Recent studies, however, underscore potential negative effects linked to intermittent fasting in teenagers. Research conducted by experts from the Technical University of Munich, LMU Hospital Munich, and Helmholtz Munich indicates that fasting in adolescence hinders the growth of pancreatic beta cells, adversely affecting insulin synthesis and increasing the risk of metabolic disorders. Intermittent fasting modifies essential physiological functions, such as insulin control, neurodevelopment, and hormonal stability. Inhibition of the mTOR pathway impedes beta\u2010cell proliferation, while glucose deficiency impacts cognitive function and psychological balance. Furthermore, intermittent fasting may exacerbate disordered eating patterns in adolescents, increasing the risk of metabolic diseases. In light of these issues, healthcare practitioners and legislators must prioritize a balanced diet and advise against uncontrolled fasting habits among teenagers. Additional study is necessary to ascertain the long\u2010term effects of intermittent fasting on human metabolic and neurological health.<\/jats:p>","DOI":"10.1111\/jgh.70077","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T05:16:26Z","timestamp":1757654186000},"page":"2770-2772","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Unveiling the Hidden Dangers of Intermittent Fasting in Adolescents: A Call for Awareness"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6598-4675","authenticated-orcid":false,"given":"Dinesh","family":"Kumar","sequence":"first","affiliation":[{"name":"School of Pharmacy Desh Bhagat University  Mandi Gobindgarh Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8533-7432","authenticated-orcid":false,"given":"Vrinda","family":"Gupta","sequence":"additional","affiliation":[{"name":"School of Pharmacy Desh Bhagat University  Mandi Gobindgarh Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-3391-2153","authenticated-orcid":false,"given":"Rajni","family":"Tanwar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences Guru Jambheswar University  Hisar Haryana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Bansal","sequence":"additional","affiliation":[{"name":"Chandigarh Group of Colleges, Jhanjeri  Mohali Punjab India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"e_1_2_1_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.115225"},{"key":"e_1_2_1_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom12050614"},{"key":"e_1_2_1_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-11639-1"},{"key":"e_1_2_1_11_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000445173"},{"key":"e_1_2_1_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/children10030516"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.70077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T20:22:22Z","timestamp":1762201342000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.70077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,11]]},"references-count":5,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/jgh.70077"],"URL":"https:\/\/doi.org\/10.1111\/jgh.70077","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,11]]},"assertion":[{"value":"2025-06-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}