{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:13:05Z","timestamp":1787015585593,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study investigated the role of the albumin\u2013bilirubin (ALBI) grade as a predictive factor for mortality in patients with favorable liver function undergoing transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 251 HCC patients with Child\u2013Pugh class A and a model for end\u2010stage liver disease (MELD) score &lt;\u200910 who received TACE as initial treatment were analyzed. Predictive factors for overall survival were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The mean age was 61.5\u2009years, and the median follow\u2010up was 10.3\u2009years. A high ALBI grade (ALBI score &gt;\u2009\u22122.60) was observed in 147 patients (59%). Multivariable analysis showed that mortality was significantly associated with Barcelona Clinic Liver Cancer (BCLC) stage B (hazard ratio [HR] 2.21, 95% confidence interval [CI] 1.24\u20133.93,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007), BCLC stage C (HR 4.80, 95% CI 2.76\u20138.34,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), presence of ascites (HR 2.28, 95% CI 1.31\u20133.97,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003), progressive disease (PD) of tumor response (HR 2.95, 95% CI 1.76\u20134.93,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and high ALBI grade (Grade \u2265\u20092) (HR 1.96, 95% CI 1.20\u20133.21,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008). Overall survival differed significantly by ALBI grade: the 3\u2010, 6\u2010, 9\u2010, and 12\u2010year survival rates were 80.4%, 78.7%, 76.2%, and 65.5% in the low ALBI group (Grade 1) and 61.3%, 42.8%, 35.7%, and 35.7% in the high ALBI group (Grade \u2265\u20092) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High ALBI grade (Grade \u2265\u20092) is associated with increased mortality in patients with Child\u2013Pugh class A and low MELD score undergoing TACE for HCC. ALBI grade may serve as a predictor of survival in patients with preserved liver function receiving TACE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.70098","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T07:28:28Z","timestamp":1759476508000},"page":"2758-2766","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Role of ALBI Grade as a Predictive Factor for Long\u2010Term Mortality in Patients With Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3463-8534","authenticated-orcid":false,"given":"Kyoung\u00a0A","family":"Ko","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyunwoo","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung\u00a0Sub","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u00a0Pyo","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong\u00a0Kyun","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung\u00a0Ik","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3284-2715","authenticated-orcid":false,"given":"Won","family":"Sohn","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30010-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v7.i3.362"},{"issue":"2","key":"e_1_2_7_5_1","first-page":"480","article-title":"Role of Transarterial Chemoembolization in the Treatment of Hepatocellular Carcinoma","volume":"11","author":"Zhong B. 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