{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:53:29Z","timestamp":1780509209470,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Accurate assessment of advanced fibrosis and steatosis is essential for prognostication in chronic liver disease. This study aimed to evaluate the diagnostic performance of MRI in assessing liver fibrosis and steatosis in patients undergoing liver transplantation (LT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who underwent LT between January 2019 and December 2023 with pretransplant MR elastography (MRE) and MRI\u2010based proton density fat fraction (MRI\u2010PDFF) examinations were included. Explanted livers were assessed for fibrosis and steatosis, with cirrhosis subclassified using the Laennec system. Diagnostic performance was evaluated using area under the receiver operating characteristic curve (AUC) analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 187 patients (median age, 57\u2009years), 72.2% were male. Hepatitis B virus (55%) and alcoholic liver disease (21.4%) were the most common etiologies. The median Model for End\u2010Stage Liver Disease (MELD) score was 11. MRE detected cirrhosis (F4) with an AUC of 0.92 (95% confidence interval [CI], 0.87\u20130.97) and severe cirrhosis (F4c) with an AUC of 0.85 (95% CI, 0.79\u20130.91), at threshold values of 4.76 and 6.43\u2009kPa, respectively. MRI\u2010PDFF identified steatosis with an AUC of 0.83 (95% CI, 0.76\u20130.89) at a threshold of 2.80%. Comparisons of patients stratified by the threshold values for cirrhosis and severe cirrhosis revealed significant differences in MELD scores, history of portal hypertension\u2010related complications, liver function parameters, and intraoperative transfusion requirements (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MRI demonstrated high diagnostic accuracy for detecting cirrhosis and steatosis in patients with advanced fibrosis undergoing LT. MRE further stratified cirrhosis severity, suggesting clinical applicability in cirrhosis staging and risk assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.70316","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T04:44:58Z","timestamp":1773463498000},"page":"1323-1334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic Value of MR Elastography and MRI\u2010Proton Density Fat Fraction in Cirrhosis Based on Explant Liver Histology"],"prefix":"10.1111","volume":"41","author":[{"given":"Eun\u2010Ki","family":"Min","sequence":"first","affiliation":[{"name":"Department of Surgery, The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung\u2010seob","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiological Science Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byungsoo","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Pathology Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9653-926X","authenticated-orcid":false,"given":"Deok\u2010Gie","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u00a0Jin","family":"Joo","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3629-4624","authenticated-orcid":false,"given":"Sang\u00a0Hoon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9658-8050","authenticated-orcid":false,"given":"Seung\u00a0Up","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6722-0257","authenticated-orcid":false,"given":"Jae\u00a0Geun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Research Institute for Transplantation Yonsei University College of Medicine  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27368"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.05.029"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2022.10.035"},{"key":"e_1_2_9_5_1","first-page":"9026","article-title":"Role of Liver Biopsy in Nonalcoholic Fatty Liver Disease","volume":"20","author":"Nalbantoglu I. 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