{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:54:03Z","timestamp":1789556043684,"version":"build-2803163510"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T00:00:00Z","timestamp":1774137600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004088","name":"Kowa Life Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim<\/jats:title>\n                    <jats:p>Computer\u2010aided detection (CADe) facilitates colorectal lesion detection, but it remains unclear whether CADe affects endoscopist's eye strain by altering gaze patterns. This study aimed to determine whether CADe\u2010assisted colonoscopy is superior to conventional colonoscopy in reducing endoscopists' gaze\u2010shift distance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center randomized controlled trial enrolled participants and randomly assigned them to two groups: first observation with CADe, then second observation without CADe (CADe\u2010first group) in the ascending colon, or observations in the reverse order (conventional\u2010first group). The endoscopist's gaze positions were recorded via a dedicated eye\u2010tracking system. The primary endpoint was the endoscopist's gaze\u2010shift distance within the first allocated group. The secondary endpoints were the gaze\u2010shift distance based on CADe experience and eye strain, ascertained using a visual analog scale (VAS) score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 59 patients that were assigned to two groups (CADe\u2010first,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200930; conventional\u2010first,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200929), there was no intergroup difference in the gaze\u2010shift distance (30.7\u2009\u00b1\u200910.7 pixels\/30\u2009ms vs. 32.7\u2009\u00b1\u20098.7 pixels\/30\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.450). Among CADe\u2010experienced endoscopists, the distance was significantly shorter in the CADe\u2010first than in the conventional\u2010first group (25.9\u2009\u00b1\u20093.4 pixels\/30\u2009ms vs. 29.4\u2009\u00b1\u20093.6 pixels\/30\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), whereas no difference was observed among CADe\u2010inexperienced endoscopists (40.3\u2009\u00b1\u200913.8 pixels\/30\u2009ms vs. 45.4\u2009\u00b1\u200911.1 pixels\/30\u2009ms,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.463). The VAS score was significantly lower in the CADe\u2010first than in the conventional\u2010first group (3.2\u2009\u00b1\u20091.2 vs. 4.6\u2009\u00b1\u20091.5,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CADe assistance did not significantly change the gaze\u2010shift distance overall, but it reduced gaze\u2010shift distance among CADe\u2010experienced endoscopists. Thus, CADe may be associated with reduced eye strain, depending on the endoscopist's CADe experience.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.70351","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:24:53Z","timestamp":1774225493000},"page":"1760-1767","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impact of Computer\u2010Aided Detection on Endoscopist's Gaze\u2010Shift Distance During Colonoscopy: a Randomized Controlled Trial (With Video)"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4208-6290","authenticated-orcid":false,"given":"Shun","family":"Ito","sequence":"first","affiliation":[{"name":"Department of Gastroenterology International University of Health and Welfare Ichikawa Hospital  Chiba Japan"},{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4065-7958","authenticated-orcid":false,"given":"Fumiaki","family":"Ishibashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology International University of Health and Welfare Ichikawa Hospital  Chiba Japan"},{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1211-9290","authenticated-orcid":false,"given":"Kosuke","family":"Okusa","sequence":"additional","affiliation":[{"name":"Department of Data Science for Business Innovation, Faculty of Science and Engineering Chuo University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2412-760X","authenticated-orcid":false,"given":"Kentaro","family":"Mochida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology International University of Health and Welfare Ichikawa Hospital  Chiba Japan"},{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8979-7800","authenticated-orcid":false,"given":"Takao","family":"Tonishi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology International University of Health and Welfare Ichikawa Hospital  Chiba Japan"},{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3766-8648","authenticated-orcid":false,"given":"Eri","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"},{"name":"Department of Gastroenterology Shinmatsudo Central General Hospital  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4831-1409","authenticated-orcid":false,"given":"Sho","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology International University of Health and Welfare Ichikawa Hospital  Chiba Japan"},{"name":"Graduate School of Medicine International University of Health and Welfare  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,22]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907667"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2006.02.021"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.7326\/M22-3678"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2024.09.003"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2020.06.021"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.16491"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11061113"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.15403\/jgld-3687"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0000000000000175"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/789038"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjophth-2018-000146"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.09.028"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.03638.x"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.05.057"},{"key":"e_1_2_14_16_1","article-title":"Eye Movement Patterns Associated With Colorectal Adenoma Detection: Post Hoc Analysis of Randomized Controlled Trial","volume":"13","author":"Ishibashi F.","year":"2025","journal-title":"Endoscopy International Open"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2019.00086"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1966-0661"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2020.04.062"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2023.10.019"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-024-11466-7"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2022.05.028"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002664"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.09.009"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-024-01334-y"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.16615"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-025-09205-6"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.70351","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgh.70351","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.70351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T14:09:05Z","timestamp":1781791745000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.70351"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,22]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/jgh.70351"],"URL":"https:\/\/doi.org\/10.1111\/jgh.70351","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,22]]},"assertion":[{"value":"2025-11-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}