{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:49:26Z","timestamp":1791917366479,"version":"4.3.4"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T00:00:00Z","timestamp":1778630400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Endoscopic ultrasound\u2010guided gallbladder drainage (EUS\u2010GBD) is the recommended treatment for high surgical risk patients with acute cholecystitis requiring drainage. Gallbladder perforation is a severe complication and is often considered a contraindication for endoscopic treatment. We report our experience with EUS\u2010GBD in patients with perforated cholecystitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analyzed consecutive cases of high surgical risk patients with acute cholecystitis and gallbladder perforation treated with EUS\u2010GBD at a tertiary referral center from September 2020 to October 2023. EUS\u2010GBD was performed using electrocautery\u2010enhanced lumen\u2010apposing metal stents (LAMS). Primary outcomes were technical and clinical success. Adverse events (AEs) were considered secondary endpoints.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve patients (50% women, mean age 75.9\u2009\u00b1\u200915.2\u2009years) were included. The median Charlson Comorbidity Index was 7. Reasons for EUS\u2010GBD included age\/comorbidities (33.3%), advanced malignancy (33.3%), and coagulopathy\/dual antiplatelet therapy (33.3%). Technical success was achieved in all patients (100%), and clinical success was observed in 11\/12 (91.7%), with significant improvement in localized and systemic infection. AEs occurred in one patient (8.33%) with pneumoperitoneum treated conservatively. The same patient experienced recurrent cholecystitis that required endoscopic stent revision 7\u2009days after the initial procedure. Median follow\u2010up was 173\u2009days (range 4\u2013820\u2009days).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EUS\u2010GBD is both technically feasible and effective for patients with acute cholecystitis and gallbladder perforation. While the AEs rate appears low, further studies are needed to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.70423","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:09:26Z","timestamp":1778717366000},"page":"2124-2129","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Endoscopic Ultrasound\u2010Guided Gallbladder Drainage in Patients at High Surgical Risk With Acute Cholecystitis and Gallbladder Perforation"],"prefix":"10.1111","volume":"41","author":[{"given":"S\u00e9bastien","family":"Godat","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5041-7660","authenticated-orcid":false,"given":"Marie","family":"Philippart","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basile","family":"Keshavjee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meddy","family":"Dalex","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Romailler","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Caillol","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Paoli\u2010Calmettes Institute  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariola","family":"Marx","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology CHUV  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,13]]},"reference":[{"issue":"5","key":"e_1_2_7_2_1","first-page":"441","article-title":"Endoscopic Ultrasound\u2010Guided Biliary Drainage and Gastrointestinal Anastomoses: The Journey From Promising Innovations to Standard of Care","volume":"35","author":"Vanella G.","year":"2022","journal-title":"Annals of Gastroenterology"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i48.7832"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.03.027"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1717-1391"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06520-y"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-021-00655-5"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319996"},{"issue":"7","key":"e_1_2_7_9_1","first-page":"404","article-title":"EUS\u2010Guided Gallbladder Drainage as a Treatment for Acute Perforated Cholecystitis","volume":"115","author":"Chavarr\u00eda C.","year":"2023","journal-title":"Revista Espa\u00f1ola de Enfermedades Digestivas"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.515"},{"issue":"4","key":"e_1_2_7_12_1","first-page":"393","article-title":"Perforations of the Gallbladder and Cholecystobiliary Fistulae: A Review of Management and a New Classification","volume":"79","author":"Anderson B. B.","year":"1987","journal-title":"Journal of the National Medical Association"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2021.11.038"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09712-x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2024.08.003"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-020-07409-7"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/eus.eus_9_18"}],"container-title":["Journal of Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.70423","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jgh.70423","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jgh.70423","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:01:38Z","timestamp":1783011698000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jgh.70423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,13]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/jgh.70423"],"URL":"https:\/\/doi.org\/10.1111\/jgh.70423","archive":["Portico"],"relation":{},"ISSN":["0815-9319","1440-1746"],"issn-type":[{"value":"0815-9319","type":"print"},{"value":"1440-1746","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,13]]},"assertion":[{"value":"2025-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}