{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:08:55Z","timestamp":1789531735246,"version":"build-2803163510"},"reference-count":53,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M750840"],"award-info":[{"award-number":["2024M750840"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Electroacupuncture (EA) reshapes intestinal flora; whether post\u2010EA fecal microbiota transplantation (post\u2010EA FMT) regulates gastrointestinal hormones via the gut microbiota\u2013bile acid (BA) pathway remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sham EA (SEA) served as control. Gastrointestinal hormones\/motility were assessed post\u2010EA. Fecal microbiota from EA\/SEA\u2010treated rats were transplanted into pseudo\u2010germ\u2010free (PGF) rats. Gut microbiota and BA profiles were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      EA downregulated Ghrelin, PYY, GLP\u20101, upregulated CCK, and enhanced motility in FD rats. Post\u2010EA FMT increased\n                      <jats:italic>Firmicutes<\/jats:italic>\n                      \/\n                      <jats:italic>Bacteroidetes<\/jats:italic>\n                      (phylum); upregulated\n                      <jats:italic>Lactobacillus<\/jats:italic>\n                      ,\n                      <jats:italic>Prevotella<\/jats:italic>\n                      ,\n                      <jats:italic>[Prevotella]<\/jats:italic>\n                      (genus); decreased\n                      <jats:italic>Blautia<\/jats:italic>\n                      ,\n                      <jats:italic>Proteobacteria<\/jats:italic>\n                      ,\n                      <jats:italic>Bacteroides<\/jats:italic>\n                      ; reduced multiple BAs (including TUDCA\/TCDCA). TUDCA\/TCDCA showed strong positive correlation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The gut microbiota\u2010BA pathway associates with post\u2010EA FMT's beneficial regulation of gastrointestinal hormones. The gut microbiota\u2013BA pathway is associated with post\u2010EA FMT's beneficial regulation of gastrointestinal hormones. The gut microbiota\u2013BA pathway is associated with post\u2010EA FMT's beneficial regulation of gastrointestinal hormones. The\n                      <jats:italic>Lactobacillus<\/jats:italic>\n                      \/TUDCA\/TCDCA axis represents a candidate pathway that may contribute to this process (validation pending). Current findings indicate strong correlations, not causality.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgh.70744","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T03:47:07Z","timestamp":1789530427000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Postelectroacupuncture Fecal Microbiota Transplantation (post\u2010EA FMT) Regulates Gastrointestinal Hormones in Functional Dyspepsia Rats Is Associated With Modulation of the Intestinal Microbiota\u2010Bile Acid Metabolic Pathway"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9673-9181","authenticated-orcid":false,"given":"Yong\u2010Li","family":"Han","sequence":"first","affiliation":[{"name":"Acupuncture Department The First Affiliated Hospital of Henan University of CM  Zhengzhou Henan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Fang","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Gastroenterology The First Affiliated Hospital of Henan University of CM  Zhengzhou Henan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli","family":"Tang","sequence":"additional","affiliation":[{"name":"College of Life Sciences Shanghai Normal University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8686-7758","authenticated-orcid":false,"given":"Dong\u2010Dong","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Acupuncture and Tuina Henan University of Chinese Medicine  Zhengzhou Henan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9895-0263","authenticated-orcid":false,"given":"Liang\u2010Yu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Spleen and Stomach The Second Affiliated Hospital of Nanjing University of Chinese Medicine  Nanjing Jiangsu Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology Henan Provincial People's Hospital and Zhengzhou University People's Hospital and Henan Provincial Key Laboratory of Neurological Disease Imaging Diagnosis and Research  Zhengzhou Henan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing\u2010Bo","family":"Wang","sequence":"additional","affiliation":[{"name":"Acupuncture Department The First Affiliated Hospital of Henan University of CM  Zhengzhou Henan Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11092342","article-title":"Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients With Functional Dyspepsia","volume":"11","author":"Aono S.","year":"2022","journal-title":"Journal of Clinical Medicine"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1053\/j.gastro.2020.04.014","article-title":"Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study","volume":"160","author":"Sperber A. 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