{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:39:04Z","timestamp":1792492744562,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Gastro and Hepatol"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Celiac disease (CeD) is an acquired immune enteropathy for which the presence of two factors, i.e., predisposing HLA genes (HLA DQ2\/DQ8) and gluten in diet are essential for induction of the pathogenic immune response. Acute symptoms\/gut injury specifically depend on the amount of gluten ingested. The incidence and prevalence of medically diagnosed CeD is expected to rise in the coming decades, and most of these people are expected to be from Asia. Through publicly available datasets, we mapped the estimated proportion of population harboring HLA DQ2\/DQ8 in different regions of Asia and the per\u2010capita gluten consumption for each country. We estimated each Asian's country's celiac risk based on these two factors and compared it with the published literature on population\u2010based serological studies from these countries. The expected trajectory of CeD and the challenges in making different countries in Asia \u201cceliac ready\u201d is discussed.<\/jats:p>","DOI":"10.1111\/jgh.70844","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:45:36Z","timestamp":1792489536000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Celiac Disease: Waiting to Explode in Asia"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2053-2069","authenticated-orcid":false,"given":"Samagra","family":"Agarwal","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8961-5455","authenticated-orcid":false,"given":"Choon Jin","family":"Ooi","sequence":"additional","affiliation":[{"name":"Duke\u2010NUS Medical School  Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert P.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Mackay Base Hospital  Mackay Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5474-9709","authenticated-orcid":false,"given":"Vineet","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2474-2194","authenticated-orcid":false,"given":"Govind K.","family":"Makharia","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Human Nutrition All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1136\/gutjnl-2021-326257","article-title":"Immunopathogenesis and Environmental Triggers in Coeliac Disease","volume":"71","author":"Levescot A.","year":"2022","journal-title":"Gut"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1365-2249.2006.03036.x","article-title":"Reduction of Tissue Transglutaminase Autoantibody Levels by Gluten\u2010Free Diet Is Associated With Changes in Subsets of Peripheral Blood Lymphocytes in Children With Newly Diagnosed Coeliac Disease","volume":"144","author":"Agardh D.","year":"2006","journal-title":"Clinical and Experimental Immunology"},{"key":"e_1_2_5_4_1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/s41575-021-00552-z","article-title":"The Global Burden of Coeliac Disease: Opportunities and Challenges","volume":"19","author":"Makharia G. 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