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Analysis of covariance models were used to determine the association between\n                      <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\n                      measures and cognitive scores at 36\u00a0months after adjusting for covariates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Greater variability in systolic (\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a0.05) but not diastolic (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&gt;\u00a0.18)\n                      <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\n                      was associated with worse global (Modified Alzheimer's Disease Assessment Scale Cognitive Component and Clinical Dementia Rating sum of boxes) and executive (Trail\u2010Making Test Part B, Animal Fluency, and Vegetable Fluency) function and episodic memory (Rey Auditory Verbal Learning Test Total Score).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      There is a clinically significant association between greater systolic\n                      <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>\n                      variability and greater cognitive dysfunction. These results should be verified in other well\u2010characterized cohorts, and the neuroanatomical pathophysiology underlying the observed greater cognitive impairment should be further explored.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.12542","type":"journal-article","created":{"date-parts":[[2013,11,25]],"date-time":"2013-11-25T17:10:44Z","timestamp":1385399444000},"page":"2168-2173","source":"Crossref","is-referenced-by-count":40,"title":["Cognitive Dysfunction and Greater Visit\u2010to\u2010Visit Systolic Blood Pressure Variability"],"prefix":"10.1111","volume":"61","author":[{"given":"Noam U.","family":"Epstein","sequence":"first","affiliation":[{"name":"Department of Neurology Hines Veterans Affairs Medical Center Hines Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Lane","sequence":"additional","affiliation":[{"name":"Division of Biostatistics School of Medicine Indiana University 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