{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:56:45Z","timestamp":1789041405567,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T00:00:00Z","timestamp":1389571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Intramural Research Program"},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To evaluate the criterion validity of two measures of fatigability, defined as performance deterioration or perceived effort to perform a standardized task.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      Cross\u2010sectional analysis of data from the\n                      <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                      altimore\n                      <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\n                      ongitudinal\n                      <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\n                      tudy of\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      ging (\n                      <jats:styled-content style=\"fixed-case\">BLSA<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>\n                      ational\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      nstitute on\n                      <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>\n                      ging,\n                      <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>\n                      ntramural\n                      <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>\n                      esearch\n                      <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>\n                      rogram,\n                      <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                      linical\n                      <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>\n                      esearch\n                      <jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>\n                      nit,\n                      <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                      altimore,\n                      <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>\n                      aryland.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      Six hundred five men (53.7%) and women aged 65 to 97 participating in the\n                      <jats:styled-content style=\"fixed-case\">BLSA<\/jats:styled-content>\n                      and eligible for endurance walk testing without a walking aid.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>\n                      Fatigability was assessed using completion status and lap times from a 400\u2010m walk performed \u201cas quickly as possible\u201d and perceived exertion rating using the\n                      <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>\n                      org scale (range 6\u201320) after 5\u00a0minutes of treadmill walking at 1.5\u00a0miles per hour (0.67\u00a0m\/s). Criterion measures included self\u2010report of tiredness, level of weakness and energy in past month, and walking ability and objective measures of usual and fast gait speed, time to complete 10 chair stands, and grip strength. Covariates included age, race, sex, obesity, smoking status, and walking activity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of mobility\u2010intact older persons, 23% exhibited performance deterioration (slowed or stopped) during the 400\u2010m walk, and one\u2010third reported more than very light exertion after a 5\u2010minute slow walk. Slowing was strongly associated with self\u2010reported fatigue and walking ability but weakly associated with performance\u2010based mobility measures. High perceived exertion was associated with tiredness, weakness, and reported and observed mobility deficits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Slowing down may have low sensitivity for identifying fatigability in older persons, but ascertaining perceived exertion during a defined workload shows promise. In seemingly healthy, motivated individuals, fatigue and fatigability were common and may affect socially meaningful mobility behaviors. Assessment of fatigability in well\u2010elderly examinations may help identify threats to independent functioning earlier in the decline process.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jgs.12638","type":"journal-article","created":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T17:06:46Z","timestamp":1389632806000},"page":"347-351","source":"Crossref","is-referenced-by-count":99,"title":["Assessing Fatigability in Mobility\u2010Intact Older Adults"],"prefix":"10.1111","volume":"62","author":[{"given":"Eleanor M.","family":"Simonsick","sequence":"first","affiliation":[{"name":"Intramural Research Program National Institute on Aging Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Schrack","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Bloomberg School of Public Health Johns Hopkins University Baltimore 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