{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:45:38Z","timestamp":1785192338282,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,10,21]],"date-time":"2014-10-21T00:00:00Z","timestamp":1413849600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Institute of Aging","award":["P30AG024827"],"award-info":[{"award-number":["P30AG024827"]}]},{"name":"National Institute of Aging","award":["K07AG033174"],"award-info":[{"award-number":["K07AG033174"]}]},{"name":"National Institute of Aging","award":["R01AG027017"],"award-info":[{"award-number":["R01AG027017"]}]},{"name":"National Institute of Aging","award":["R01AG037451"],"award-info":[{"award-number":["R01AG037451"]}]},{"name":"Veterans Affairs Health Services Research and Development Service","award":["IIR 12-379"],"award-info":[{"award-number":["IIR 12-379"]}]},{"name":"Veterans Affairs Health Services Research and Development Service","award":["P30AG028716"],"award-info":[{"award-number":["P30AG028716"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J American Geriatrics Society"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:p>The objective of this paper is to review articles published in 2013 examining drug\u2010related problems in the elderly and comment on their potential impact on clinical practice. To identify articles, we did a systematic search of the English\u2010language literature restricted to those aged 65\u00a0+\u00a0from January 2013 to December 2013 using Medline and Google Scholar and a combination of the following search terms: drug\u2010related problems, medication\u2010related problems, medication errors, suboptimal prescribing, inappropriate prescribing, underutilization, polypharmacy, medication monitoring, medication dispensing, medication administration, medication adherence, adverse drug events, and adverse drug withdrawal events. A manual search of major general medicine and clinical pharmacology journals was also conducted to identify additional articles. A total of 51 articles were identified of which 20 were chosen to highlight. Three were annotated and critiqued and the additional 17 articles were summarized in an appendix. One article reported the results of a randomized controlled trial that showed that a pharmacist intervention successfully reduced suboptimal prescribing in older hospital patients. Another paper from this group previously reported data from the same study showing that the intervention also reduced medication related readmissions to the hospital. An observational study compared the use of two thiazide diuretics in older outpatients. They found that chlorthalidone was more likely to cause hypokalemia than hydrochlorothiazide. Finally, in a randomized controlled trial a pharmacist intervention resulted in the reduction of anticholinergic burden but did result in an improvement in cognition. These studies highlight that medication errors and adverse drug events continue to be important issues for health care professionals caring for older adults.<\/jats:p>","DOI":"10.1111\/jgs.13026","type":"journal-article","created":{"date-parts":[[2015,1,30]],"date-time":"2015-01-30T09:40:09Z","timestamp":1422610809000},"page":"1950-1953","source":"Crossref","is-referenced-by-count":9,"title":["Medication Misadventures in Older Adults: Literature from 2013"],"prefix":"10.1111","volume":"62","author":[{"given":"Joseph T.","family":"Hanlon","sequence":"first","affiliation":[{"name":"Division of Geriatrics Department of Medicine School of Medicine University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Department of Biomedical Informatics School of Medicine University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Department of Pharmacy and Therapeutics School of Pharmacy University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Department of Epidemiology School of Public Health University of Pittsburgh Pittsburgh Pennsylvania"},{"name":"Geriatric Pharmaceutical Outcomes and Gero\u2010Informatics Research and Training Program University of Pittsburgh Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd P.","family":"Semla","sequence":"additional","affiliation":[{"name":"Pharmacy Benefits Management Services Department of Veterans Affairs Hines Illinois"},{"name":"Department of Medicine Feinberg School of Medicine Northwestern University Chicago Illinois"},{"name":"Department of Psychiatry and Behavioral Science Feinberg School of Medicine Northwestern University Chicago Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth E.","family":"Schmader","sequence":"additional","affiliation":[{"name":"Division of Geriatrics Department of Medicine School of Medicine Duke University Medical Center Durham North Carolina"},{"name":"Geriatric Research Education and Clinical Center Durham Veterans Affairs 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